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Mendeley readers
Chapter title |
Disulfide-Bridged Cleavable PEGylation of Poly- l -Lysine for SiRNA Delivery
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Chapter number | 5 |
Book title |
SiRNA Delivery Methods
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Published in |
Methods in molecular biology, January 2016
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DOI | 10.1007/978-1-4939-3112-5_5 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3111-8, 978-1-4939-3112-5
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Authors |
Min Tang, Haiqing Dong, Xiaojun Cai, Haiyan Zhu, Tianbin Ren, Yongyong Li, Tang, Min, Dong, Haiqing, Cai, Xiaojun, Zhu, Haiyan, Ren, Tianbin, Li, Yongyong |
Abstract |
Engineered PEG-cleavable catiomers based on poly-L-lysine have been developed as nonviral gene vectors, which have been found to be one of important methods to balance "PEG dilemma." In this protocol, we aim at the standardization of the method and procedure of PEG-cleavable catiomers. Major steps including ring-opening polymerization (ROP) of ε-benzyloxycarbonyl-L-lysine N-carboxyanhydride (zLL-NCA) monomers to yield PEG-cleavable polylysine, examination on bio-stability and bio-efficacy of its gene complexes are described. |
Mendeley readers
The data shown below were compiled from readership statistics for 2 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 1 | 50% |
Unknown | 1 | 50% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 1 | 50% |
Unknown | 1 | 50% |