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Mendeley readers
| Chapter title |
Nitric Oxide-Mediated Pain Processing in the Spinal Cord
|
|---|---|
| Chapter number | 6 |
| Book title |
Pain Control
|
| Published in |
Handbook of experimental pharmacology, January 2015
|
| DOI | 10.1007/978-3-662-46450-2_6 |
| Pubmed ID | |
| Book ISBNs |
978-3-66-246449-6, 978-3-66-246450-2
|
| Authors |
Achim Schmidtko, Schmidtko, Achim |
| Abstract |
A large body of evidence indicates that nitric oxide (NO) plays an important role in the processing of persistent inflammatory and neuropathic pain in the spinal cord. Several animal studies revealed that inhibition or knockout of NO synthesis ameliorates persistent pain. However, spinal delivery of NO donors caused dual pronociceptive and antinociceptive effects, pointing to multiple downstream signaling mechanisms of NO. This review summarizes the localization and function of NO-dependent signaling mechanisms in the spinal cord, taking account of the recent progress made in this field. |
Mendeley readers
The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 21 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 4 | 19% |
| Student > Ph. D. Student | 4 | 19% |
| Student > Master | 3 | 14% |
| Researcher | 3 | 14% |
| Student > Bachelor | 2 | 10% |
| Other | 3 | 14% |
| Unknown | 2 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 8 | 38% |
| Medicine and Dentistry | 5 | 24% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 10% |
| Chemical Engineering | 1 | 5% |
| Computer Science | 1 | 5% |
| Other | 0 | 0% |
| Unknown | 4 | 19% |