Chapter title |
Platelet Function Tests: Preanalytical Variables, Clinical Utility, Advantages, and Disadvantages
|
---|---|
Chapter number | 24 |
Book title |
Hemostasis and Thrombosis
|
Published in |
Methods in molecular biology, January 2017
|
DOI | 10.1007/978-1-4939-7196-1_24 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7194-7, 978-1-4939-7196-1
|
Authors |
Anne-Mette Hvas, Erik Lerkevang Grove, Hvas, Anne-Mette, Grove, Erik Lerkevang |
Abstract |
Platelet function tests are mainly used in the diagnostic work-up of platelet disorders. During the last decade, the additional use of platelet function tests to evaluate the effect of antiplatelet therapy has also emerged in an attempt to identify patients with an increased risk of arterial thrombosis. Furthermore, platelet function tests are increasingly used to measure residual effect of antiplatelet therapy prior to surgery with the aim of reducing the risk of bleeding. To a limited extend, platelet function tests are also used to evaluate hyperaggregability as a potential marker of a prothrombotic state outside the setting of antiplatelet therapy. This multifaceted use of platelet function tests and the development of simpler point-of-care tests with narrower application have increased the use of platelet function testing and also facilitated the use of platelet function tests outside the highly specialized laboratories. The present chapter describes the preanalytical variables, which should be taken into account when planning platelet function testing. Also, the most widely used platelet function tests are introduced, and their clinical utility and their relative advantages and disadvantages are discussed. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 30 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 13% |
Student > Master | 3 | 10% |
Student > Doctoral Student | 2 | 7% |
Lecturer > Senior Lecturer | 2 | 7% |
Researcher | 2 | 7% |
Other | 4 | 13% |
Unknown | 13 | 43% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 33% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Nursing and Health Professions | 1 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Psychology | 1 | 3% |
Other | 1 | 3% |
Unknown | 15 | 50% |