Chapter title |
Signaling Pathway in Early Brain Injury after Subarachnoid Hemorrhage: News Update.
|
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Chapter number | 21 |
Book title |
Brain Edema XVI
|
Published in |
Acta neurochirurgica Supplement, January 2016
|
DOI | 10.1007/978-3-319-18497-5_21 |
Pubmed ID | |
Book ISBNs |
978-3-31-918496-8, 978-3-31-918497-5
|
Authors |
Ji, Chengyuan, Chen, Gang, Chengyuan Ji, Gang Chen |
Abstract |
The annual incidence of subarachnoid hemorrhage (SAH) caused by intracranial aneurysm rupture is approximately 10.5/10 million people in China, making SAH the third most frequently occurring hemorrhage of the intracranial type after cerebral embolism and hypertensive intracerebral hemorrhage. SAH caused by ruptured aneurysm leads to a mortality rate as high as 67 %, and, because of the sudden onset of this disease, approximately 12-15 % of patients die before they can receive effective treatment. Early brain injury (EBI) is the brain damage occurring within the first 72 h after SAH. Two-thirds of mortality caused by SAH occurs within 48 h, mainly as a result of EBI. With the development of molecular biology and medicine microscopy techniques, various signaling pathways involved in EBI after SAH have been revealed. Understanding these signaling pathways may help clinicians treat EBI after SAH and improve long-term prognosis of SAH patients. This chapter summarizes several important signaling pathways implicated in EBI caused by SAH. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Poland | 1 | 6% |
Unknown | 15 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 2 | 13% |
Student > Doctoral Student | 1 | 6% |
Professor | 1 | 6% |
Other | 1 | 6% |
Student > Master | 1 | 6% |
Other | 3 | 19% |
Unknown | 7 | 44% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 6 | 38% |
Biochemistry, Genetics and Molecular Biology | 2 | 13% |
Neuroscience | 1 | 6% |
Unknown | 7 | 44% |