You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
| Chapter title |
Chromosome Painting of Mouse Chromosomes
|
|---|---|
| Chapter number | 13 |
| Book title |
Mouse Embryogenesis
|
| Published in |
Methods in molecular biology, January 2018
|
| DOI | 10.1007/978-1-4939-7714-7_13 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7713-0, 978-1-4939-7714-7
|
| Authors |
Lisa L. Hua, Takashi Mikawa |
| Abstract |
Chromosome painting enables the visualization of chromosomes and has been used extensively in cytogenetics. Chromosome paint probes, which consist of a pooled composite of DNA-FISH probes, bind to nonrepetitive sequences for individual chromosomes [1, 2]. Here we describe the process of using chromosome paint to study the organization of chromosomes without fragmenting the nucleus. This method can be used to analyze chromosome position, and identify translocations and ploidy within the nucleus. The preservation of nuclear morphology is crucial in understanding interchromosomal interactions and dynamics in the nucleus during the cell cycle. |
Mendeley readers
The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 12 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 2 | 17% |
| Student > Ph. D. Student | 2 | 17% |
| Unspecified | 1 | 8% |
| Student > Bachelor | 1 | 8% |
| Student > Master | 1 | 8% |
| Other | 1 | 8% |
| Unknown | 4 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 33% |
| Unspecified | 1 | 8% |
| Veterinary Science and Veterinary Medicine | 1 | 8% |
| Agricultural and Biological Sciences | 1 | 8% |
| Chemistry | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 4 | 33% |