Chapter title |
Evaluation of Tumor Cell Invasiveness In Vivo: The Chick Chorioallantoic Membrane Assay
|
---|---|
Chapter number | 8 |
Book title |
Cell Migration
|
Published in |
Methods in molecular biology, March 2018
|
DOI | 10.1007/978-1-4939-7701-7_8 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7700-0, 978-1-4939-7701-7
|
Authors |
Selma Maacha, Simon Saule |
Abstract |
Metastases is largely responsible for the mortality among cancer patients. Metastasis formation is a complex multistep process, which results from the propagation of cancer cells from the primary tumor to distant sites of the body. Research on cancer metastasis aims to understand the mechanisms involved in the spread of cancer cells through the development of in vivo assays that assess cell invasion. Here we describe the use of the chick chorioallantoic membrane to evaluate cancer cell invasiveness in vivo. The chick chorioallantoic membrane assay is based on the detection and quantification of disseminated human tumor cells in the chick embryo femurs by real-time PCR amplification of human Alu sequences. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 19 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 3 | 16% |
Student > Master | 3 | 16% |
Student > Ph. D. Student | 3 | 16% |
Student > Postgraduate | 2 | 11% |
Student > Bachelor | 1 | 5% |
Other | 2 | 11% |
Unknown | 5 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 6 | 32% |
Agricultural and Biological Sciences | 3 | 16% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Social Sciences | 1 | 5% |
Medicine and Dentistry | 1 | 5% |
Other | 2 | 11% |
Unknown | 5 | 26% |