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Mendeley readers
| Chapter title |
Imaging Translation Dynamics of Single mRNA Molecules in Live Cells
|
|---|---|
| Chapter number | 26 |
| Book title |
RNA Detection
|
| Published in |
Methods in molecular biology, January 2018
|
| DOI | 10.1007/978-1-4939-7213-5_26 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7212-8, 978-1-4939-7213-5
|
| Authors |
Suzan Ruijtenberg, Tim A. Hoek, Xiaowei Yan, Marvin E. Tanenbaum |
| Abstract |
mRNA translation is a key step in decoding the genetic information stored in DNA. Regulation of translation efficiency contributes to gene expression control and is therefore important for cell fate and function. Here, we describe a recently developed microscopy-based method that allows for visualization of translation of single mRNAs in live cells. The ability to measure translation dynamics of single mRNAs will enable a better understanding of spatiotemporal control of translation, and will provide unique insights into translational heterogeneity of different mRNA molecules in single cells. |
Mendeley readers
The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 34 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 24% |
| Student > Master | 6 | 18% |
| Student > Bachelor | 3 | 9% |
| Researcher | 3 | 9% |
| Student > Postgraduate | 3 | 9% |
| Other | 6 | 18% |
| Unknown | 5 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 11 | 32% |
| Agricultural and Biological Sciences | 5 | 15% |
| Neuroscience | 4 | 12% |
| Medicine and Dentistry | 2 | 6% |
| Social Sciences | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 8 | 24% |