Chapter title |
Guidelines to Compose an Ideal Bacteriophage Cocktail
|
---|---|
Chapter number | 9 |
Book title |
Bacteriophage Therapy
|
Published in |
Methods in molecular biology, November 2017
|
DOI | 10.1007/978-1-4939-7395-8_9 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7394-1, 978-1-4939-7395-8
|
Authors |
Maia Merabishvili, Jean-Paul Pirnay, Daniel De Vos, Merabishvili, Maia, Pirnay, Jean-Paul, De Vos, Daniel, Vos, Daniel |
Abstract |
Correctly designed bacteriophage therapeutics are the cornerstone for a successful outcome of bacteriophage therapy. Here we overview strategies on how to choose bacteriophages and their bacterial hosts at different steps of a bacteriophage cocktail development in order to comply with all quality and safety requirements based on the already existing essentially empirical experience in bacteriophage therapy and current accomplishments in modern biomedical sciences. A modification of the classic Appelmans' method (1922) to assess stability of bacteriophage activity in liquid media is presented in order to improve the overall performance of therapeutic bacteriophages individually and collectively in the cocktail. |
X Demographics
Geographical breakdown
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 98 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 12 | 12% |
Student > Ph. D. Student | 11 | 11% |
Student > Bachelor | 11 | 11% |
Researcher | 10 | 10% |
Other | 5 | 5% |
Other | 10 | 10% |
Unknown | 39 | 40% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 15 | 15% |
Agricultural and Biological Sciences | 13 | 13% |
Immunology and Microbiology | 12 | 12% |
Medicine and Dentistry | 7 | 7% |
Computer Science | 2 | 2% |
Other | 4 | 4% |
Unknown | 45 | 46% |