Chapter title |
Metabolomics, Lipidomics and Pharmacometabolomics of Human Hypertension
|
---|---|
Chapter number | 79 |
Book title |
Hypertension: from basic research to clinical practice
|
Published in |
Advances in experimental medicine and biology, January 2016
|
DOI | 10.1007/5584_2016_79 |
Pubmed ID | |
Book ISBNs |
978-3-31-944250-1, 978-3-31-944251-8
|
Authors |
Anthony Au, Kian-Kai Cheng, Loo Keat Wei |
Abstract |
Hypertension is a common but complex human disease, which can lead to a heart attack, stroke, kidney disease or other complications. Since the pathogenesis of hypertension is heterogeneous and multifactorial, it is crucial to establish a comprehensive metabolomic approach to elucidate the molecular mechanism of hypertension. Although there have been limited metabolomic, lipidomic and pharmacometabolomic studies investigating this disease to date, metabolomic studies on hypertension have provided greater insights into the identification of disease-specific biomarkers, predicting treatment outcome and monitor drug safety and efficacy. Therefore, we discuss recent updates on the applications of metabolomics technology in human hypertension with a focus on metabolic biomarker discovery. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 36 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 7 | 19% |
Student > Master | 5 | 14% |
Lecturer | 3 | 8% |
Student > Doctoral Student | 2 | 6% |
Student > Ph. D. Student | 2 | 6% |
Other | 4 | 11% |
Unknown | 13 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 6 | 17% |
Medicine and Dentistry | 5 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Chemistry | 2 | 6% |
Computer Science | 1 | 3% |
Other | 3 | 8% |
Unknown | 17 | 47% |