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Mendeley readers
| Chapter title |
Discovery and Roles of ER-Endolysosomal Contact Sites in Disease
|
|---|---|
| Chapter number | 10 |
| Book title |
Organelle Contact Sites
|
| Published in |
Advances in experimental medicine and biology, January 2017
|
| DOI | 10.1007/978-981-10-4567-7_10 |
| Pubmed ID | |
| Book ISBNs |
978-9-81-104566-0, 978-9-81-104567-7
|
| Authors |
William Mike Henne, Henne, William Mike |
| Abstract |
Inter-organelle membrane contact sites (MCSs) serve as unique microenvironments for the sensing and exchange of cellular metabolites and lipids. Though poorly defined, ER-endolysosomal contact sites are quickly becoming recognized as centers for inter-organelle lipid exchange and metabolic decision-making. Here, we review the discovery and current state of knowledge of ER-endolysosomal MCSs with particular focus on the molecular players that establish and/or utilize these contact sites in metabolism. We also discuss associations of ER-endolysosomal MCS-associated proteins in human disease, as well as the therapeutic promise these contact sites hold in modulating cellular physiology. |
Mendeley readers
The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 40 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 20% |
| Student > Doctoral Student | 7 | 18% |
| Student > Master | 4 | 10% |
| Researcher | 3 | 8% |
| Professor | 2 | 5% |
| Other | 4 | 10% |
| Unknown | 12 | 30% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 12 | 30% |
| Agricultural and Biological Sciences | 8 | 20% |
| Neuroscience | 5 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
| Chemistry | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 13 | 33% |