| Chapter title |
Ceramide Transport from the Endoplasmic Reticulum to the Trans Golgi Region at Organelle Membrane Contact Sites
|
|---|---|
| Chapter number | 5 |
| Book title |
Organelle Contact Sites
|
| Published in |
Advances in experimental medicine and biology, January 2017
|
| DOI | 10.1007/978-981-10-4567-7_5 |
| Pubmed ID | |
| Book ISBNs |
978-9-81-104566-0, 978-9-81-104567-7
|
| Authors |
Kentaro Hanada, Hanada, Kentaro |
| Abstract |
Lipids are the major constituents of all cell membranes and play dynamic roles in organelle structure and function. Although the spontaneous transfer of lipids between different membranes rarely occurs, lipids are appropriately transported between different organelles for their metabolism and to exert their functions in living cells. Proteins that have the biochemical capability to catalyze the intermembrane transfer of lipids are called lipid transfer proteins (LTPs). All organisms possess many types of LTPs. Recent studies revealed that LTPs are key players in the interorganelle transport of lipids at organelle membrane contact sites (MCSs). This chapter depicts how LTPs rationally operate at MCSs by using the ceramide transport protein CERT as a typical model for the LTP-mediated interorganelle transport of lipids. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 18 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 28% |
| Student > Bachelor | 3 | 17% |
| Lecturer > Senior Lecturer | 2 | 11% |
| Researcher | 2 | 11% |
| Student > Master | 2 | 11% |
| Other | 1 | 6% |
| Unknown | 3 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 9 | 50% |
| Agricultural and Biological Sciences | 1 | 6% |
| Computer Science | 1 | 6% |
| Immunology and Microbiology | 1 | 6% |
| Medicine and Dentistry | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 4 | 22% |