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Long Non Coding RNA Biology

Overview of attention for book
Attention for Chapter 2: Long Noncoding RNA: Genome Organization and Mechanism of Action
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

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1 blog
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1 X user

Citations

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39 Dimensions

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86 Mendeley
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Chapter title
Long Noncoding RNA: Genome Organization and Mechanism of Action
Chapter number 2
Book title
Long Non Coding RNA Biology
Published in
Advances in experimental medicine and biology, January 2017
DOI 10.1007/978-981-10-5203-3_2
Pubmed ID
Book ISBNs
978-9-81-105202-6, 978-9-81-105203-3
Authors

Vijay Suresh Akhade, Debosree Pal, Chandrasekhar Kanduri

Abstract

For the last four decades, we have known that noncoding RNAs maintain critical housekeeping functions such as transcription, RNA processing, and translation. However, in the late 1990s and early 2000s, the advent of high-throughput sequencing technologies and computational tools to analyze these large sequencing datasets facilitated the discovery of thousands of small and long noncoding RNAs (lncRNAs) and their functional role in diverse biological functions. For example, lncRNAs have been shown to regulate dosage compensation, genomic imprinting, pluripotency, cell differentiation and development, immune response, etc. Here we review how lncRNAs bring about such copious functions by employing diverse mechanisms such as translational inhibition, mRNA degradation, RNA decoys, facilitating recruitment of chromatin modifiers, regulation of protein activity, regulating the availability of miRNAs by sponging mechanism, etc. In addition, we provide a detailed account of different mechanisms as well as general principles by which lncRNAs organize functionally different nuclear sub-compartments and their impact on nuclear architecture.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 86 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 21%
Student > Master 13 15%
Researcher 10 12%
Student > Bachelor 9 10%
Student > Doctoral Student 8 9%
Other 6 7%
Unknown 22 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 38 44%
Agricultural and Biological Sciences 11 13%
Medicine and Dentistry 7 8%
Immunology and Microbiology 3 3%
Engineering 2 2%
Other 1 1%
Unknown 24 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 August 2017.
All research outputs
#4,115,649
of 22,997,544 outputs
Outputs from Advances in experimental medicine and biology
#673
of 4,960 outputs
Outputs of similar age
#82,150
of 421,196 outputs
Outputs of similar age from Advances in experimental medicine and biology
#60
of 490 outputs
Altmetric has tracked 22,997,544 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,960 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.1. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 421,196 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 490 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.