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Chapter title |
Angiogenesis Model of Cornea to Understand the Role of Sphingosine 1-Phosphate
|
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Chapter number | 23 |
Book title |
Lipidomics
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Published in |
Methods in molecular biology, June 2017
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DOI | 10.1007/978-1-4939-6996-8_23 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6995-1, 978-1-4939-6996-8
|
Authors |
Joseph L. Wilkerson, Nawajes A. Mandal |
Editors |
Sanjoy K. Bhattacharya |
Abstract |
The role of sphingolipids, mainly sphingosine 1-phosphate (S1P) and the receptors for which it serves as a ligand, is an interesting and promising area in both sphingolipid and vascular biology. S1P is crucial for establishing blood flow competent blood vessels (Jung et al. Dev Cell 23(3):600-610, 2012). The role of S1P in neovascular pathology is of great interest and promising as a target for treatment. Here we describe an easy and affordable in vivo model of neovascularization by an alkali chemical burn to the cornea. This gives a consistent and easy way to quantitate methods for neovascularization. |
Mendeley readers
The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 7 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Unspecified | 2 | 29% |
Professor | 1 | 14% |
Student > Ph. D. Student | 1 | 14% |
Student > Master | 1 | 14% |
Unknown | 2 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Unspecified | 2 | 29% |
Neuroscience | 1 | 14% |
Chemistry | 1 | 14% |
Medicine and Dentistry | 1 | 14% |
Unknown | 2 | 29% |