| Chapter title |
Eating Disorders and Epigenetics
|
|---|---|
| Chapter number | 5 |
| Book title |
Neuroepigenomics in Aging and Disease
|
| Published in |
Advances in experimental medicine and biology, May 2017
|
| DOI | 10.1007/978-3-319-53889-1_5 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-953888-4, 978-3-31-953889-1, 978-3-31-953888-4, 978-3-31-953889-1
|
| Authors |
Thaler, Lea, Steiger, Howard, Lea Thaler Ph.D., Howard Steiger Ph.D., Lea Thaler, Howard Steiger |
| Editors |
Raul Delgado-Morales |
| Abstract |
Eating disorders (EDs) are characterized by intense preoccupation with shape and weight and maladaptive eating practices. The complex of symptoms that characterize EDs often arise through the activation of latent genetic potentials by environmental exposures, and epigenetic mechanisms are believed to link environmental exposures to gene expression. This chapter provides an overview of genetic factors acting in the etiology of EDs. It then provides a background to the hypothesis that epigenetic mechanisms link stresses such as obstetric complications and childhood abuse as well as effects of malnutrition to eating disorders (EDs). The chapter then summarizes the emerging body of literature on epigenetics and EDs-mainly studies on DNA methylation in samples of anorexia and bulimia. The available evidence base suggests that an epigenetically informed perspective contributes in valuable ways to the understanding of why people develop EDs. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 33% |
| Canada | 1 | 17% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Scientists | 1 | 17% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 102 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 16% |
| Student > Master | 13 | 13% |
| Researcher | 9 | 9% |
| Other | 7 | 7% |
| Student > Postgraduate | 5 | 5% |
| Other | 20 | 20% |
| Unknown | 32 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 16% |
| Psychology | 13 | 13% |
| Nursing and Health Professions | 9 | 9% |
| Biochemistry, Genetics and Molecular Biology | 7 | 7% |
| Social Sciences | 4 | 4% |
| Other | 15 | 15% |
| Unknown | 38 | 37% |