Chapter title |
In Silico Prediction of RNA Secondary Structure
|
---|---|
Chapter number | 7 |
Book title |
Promoter Associated RNA
|
Published in |
Methods in molecular biology, March 2017
|
DOI | 10.1007/978-1-4939-6716-2_7 |
Pubmed ID | |
Book ISBNs |
978-1-4939-6714-8, 978-1-4939-6716-2
|
Authors |
Fariza Tahi, Van Du T. Tran, Anouar Boucheham |
Editors |
Sara Napoli |
Abstract |
The secondary structure of an RNA molecule represents the base-pairing interactions within the molecule and fundamentally determines its overall structure. In this chapter, we overview the main approaches and existing tools for predicting RNA secondary structures, as well as methods for identifying noncoding RNAs from genomic sequences or RNA sequencing data. We then focus on the identification of a well-known class of small noncoding RNAs, namely microRNAs, which play very important roles in many biological processes through regulating post-transcriptionally the expression of genes and which dysregulation has been shown to be involved in several human diseases. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 23% |
Student > Master | 5 | 23% |
Researcher | 3 | 14% |
Student > Ph. D. Student | 3 | 14% |
Other | 2 | 9% |
Other | 2 | 9% |
Unknown | 2 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 10 | 45% |
Agricultural and Biological Sciences | 5 | 23% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 14% |
Chemistry | 2 | 9% |
Medicine and Dentistry | 1 | 5% |
Other | 0 | 0% |
Unknown | 1 | 5% |