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Drug Discovery from Mother Nature

Overview of attention for book
Attention for Chapter 18: Eucalyptol and Its Role in Chronic Diseases
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

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4 X users
facebook
3 Facebook pages
video
1 YouTube creator

Citations

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26 Dimensions

Readers on

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133 Mendeley
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Chapter title
Eucalyptol and Its Role in Chronic Diseases
Chapter number 18
Book title
Drug Discovery from Mother Nature
Published in
Advances in experimental medicine and biology, October 2016
DOI 10.1007/978-3-319-41342-6_18
Pubmed ID
Book ISBNs
978-3-31-941341-9, 978-3-31-941342-6
Authors

Seol, Geun Hee, Kim, Ka Young, Geun Hee Seol, Ka Young Kim

Editors

Subash Chandra Gupta, Sahdeo Prasad, Bharat B. Aggarwal

Abstract

Patients with chronic diseases such as cardiovascular diseases, chronic respiratory diseases, and neurological diseases have been shown to benefit from treatments such as aromatherapy in addition to medication. Most chronic diseases are caused by chronic inflammation and oxidative stress as well as harmful factors. Eucalyptol (1,8-cineole), a terpenoid oxide isolated from Eucalyptus species, is a promising compound for treating such conditions as it has been shown to have anti-inflammatory and antioxidant effects in various diseases, including respiratory disease, pancreatitis, colon damage, and cardiovascular and neurodegenerative diseases. Eucalyptol suppresses lipopolysaccharide (LPS)-induced proinflammatory cytokine production through the action of NF-κB, TNF-α, IL-1β, and IL-6 and the extracellular signal-regulated kinase (ERK) pathway, and reduces oxidative stress through the regulation of signaling pathways and radical scavenging. The effects of eucalyptol have been studied in several cell and animal models as well as in patients with chronic diseases. Furthermore, eucalyptol can pass the blood-brain barrier and hence can be used as a carrier to deliver drugs to the brain via a microemulsion system. In summary, the various biological activities of eucalyptol such as its anti-inflammatory and antioxidant properties, as well as its physicochemical characteristics, make this compound a potentially important drug for the treatment of chronic diseases.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 133 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 12%
Student > Master 16 12%
Student > Bachelor 11 8%
Student > Doctoral Student 6 5%
Researcher 6 5%
Other 16 12%
Unknown 62 47%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 9%
Medicine and Dentistry 12 9%
Pharmacology, Toxicology and Pharmaceutical Science 11 8%
Biochemistry, Genetics and Molecular Biology 7 5%
Chemistry 6 5%
Other 18 14%
Unknown 67 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 May 2020.
All research outputs
#6,407,374
of 23,335,153 outputs
Outputs from Advances in experimental medicine and biology
#1,000
of 4,995 outputs
Outputs of similar age
#96,818
of 316,598 outputs
Outputs of similar age from Advances in experimental medicine and biology
#20
of 81 outputs
Altmetric has tracked 23,335,153 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 4,995 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,598 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.