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Drug Discovery from Mother Nature

Overview of attention for book
Attention for Chapter 3: Eugenol and Its Role in Chronic Diseases
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog

Citations

dimensions_citation
26 Dimensions

Readers on

mendeley
105 Mendeley
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Chapter title
Eugenol and Its Role in Chronic Diseases
Chapter number 3
Book title
Drug Discovery from Mother Nature
Published in
Advances in experimental medicine and biology, October 2016
DOI 10.1007/978-3-319-41342-6_3
Pubmed ID
Book ISBNs
978-3-31-941341-9, 978-3-31-941342-6
Authors

S. Fujisawa, Y. Murakami, Fujisawa, S., Murakami, Y.

Editors

Subash Chandra Gupta, Sahdeo Prasad, Bharat B. Aggarwal

Abstract

The active components in cloves are eugenol and isoeugenol. Eugenol has recently become a focus of interest because of its potential role in alleviating and preventing chronic diseases such as cancer, inflammatory reactions, and other conditions. The radical-scavenging and anti-inflammatory activities of eugenol have been shown to modulate chronic diseases in vitro and in vivo, but in humans, the therapeutic use of eugenol still remains to be explored. Based on a review of the recent literature, the antioxidant, anti-proliferative, and anti-inflammatory activities of eugenol and its related compounds are discussed in relation to experimentally determined antioxidant activity (stoichiometric factor n and inhibition rate constant) and theoretical parameters [phenolic O-H bond dissociation enthalpy (BDE), ionization potential (IP according to Koopman's theorem), and electrophilicity (ω)], calculated using a density functional theory method. Dimers of eugenol and its related compounds showed large antioxidant activities and high ω values and also exerted efficient anti-inflammatory activities. Eugenol appears to possess multiple antioxidant activities (dimerization, recycling, and chelating effect) in one molecule, thus having the potential to alleviate and prevent chronic diseases.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 105 100%

Demographic breakdown

Readers by professional status Count As %
Unspecified 9 9%
Student > Master 8 8%
Student > Bachelor 8 8%
Student > Ph. D. Student 7 7%
Student > Postgraduate 6 6%
Other 17 16%
Unknown 50 48%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 11 10%
Medicine and Dentistry 9 9%
Unspecified 9 9%
Agricultural and Biological Sciences 7 7%
Nursing and Health Professions 4 4%
Other 13 12%
Unknown 52 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 December 2022.
All research outputs
#2,344,487
of 23,283,373 outputs
Outputs from Advances in experimental medicine and biology
#349
of 4,991 outputs
Outputs of similar age
#42,512
of 316,487 outputs
Outputs of similar age from Advances in experimental medicine and biology
#8
of 80 outputs
Altmetric has tracked 23,283,373 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,991 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,487 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.