| Chapter title |
Fluorescence and Bioluminescence Imaging of Orthotopic Brain Tumors in Mice
|
|---|---|
| Chapter number | 17 |
| Book title |
Cancer Nanotechnology
|
| Published in |
Methods in molecular biology, February 2017
|
| DOI | 10.1007/978-1-4939-6646-2_17 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-6644-8, 978-1-4939-6646-2
|
| Authors |
Emilie McKinnon, Alfred Moore, Suraj Dixit, Yun Zhu, Ann-Marie Broome Ph.D., M.B.A., Ann-Marie Broome |
| Editors |
Reema Zeineldin |
| Abstract |
Optical imaging strategies, such as fluorescence and bioluminescence imaging, are non-invasive, in vivo whole body imaging techniques utilized to study cancer. Optical imaging is widely used in preclinical work because of its ease of use and cost-friendliness. It also provides the opportunity to study animals and biological responses longitudinally over time. Important considerations include depth of tissue penetration, photon scattering, absorption and the choice of light emitting probe, all of which affect the resolution (image quality and data information) and the signal to noise ratio of the image. We describe how to use bioluminescence and fluorescence imaging to track a chemotherapeutic delivery nanocarrier conjugated with a fluorophore to determine its localization in vivo. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 5 | 29% |
| Researcher | 2 | 12% |
| Student > Bachelor | 2 | 12% |
| Student > Ph. D. Student | 2 | 12% |
| Other | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 4 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 29% |
| Agricultural and Biological Sciences | 3 | 18% |
| Biochemistry, Genetics and Molecular Biology | 2 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 12% |
| Psychology | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 4 | 24% |