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Microchip Diagnostics

Overview of attention for book
Cover of 'Microchip Diagnostics'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Microfluidics-Enabled Diagnostic Systems: Markets, Challenges, and Examples.
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    Chapter 2 Capillary-Driven Microfluidic Chips for Miniaturized Immunoassays: Efficient Fabrication and Sealing of Chips Using a "Chip-Olate" Process.
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    Chapter 3 Capillary-Driven Microfluidic Chips for Miniaturized Immunoassays: Patterning Capture Antibodies Using Microcontact Printing and Dry-Film Resists.
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    Chapter 4 Fabrication and Evaluation of Microfluidic Immunoassay Devices with Antibody-Immobilized Microbeads Retained in Porous Hydrogel Micropillars.
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    Chapter 5 Using Electrophoretic Immunoassay to Monitor Hormone Secretion.
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    Chapter 6 On-Chip Magnetic Particle-Based Immunoassays Using Multilaminar Flow for Clinical Diagnostics.
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    Chapter 7 Digital Microfluidics Assisted Sealing of Individual Magnetic Particles in Femtoliter-Sized Reaction Wells for Single-Molecule Detection.
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    Chapter 8 Microfluidic DNA Stretching Device for Single-Molecule Diagnostics.
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    Chapter 9 Droplet Microfluidic and Magnetic Particles Platform for Cancer Typing.
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    Chapter 10 SlipChip Device for Digital Nucleic Acid Amplification.
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    Chapter 11 Multiplex Detection of KRAS Mutations Using Passive Droplet Fusion.
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    Chapter 12 Droplet-Based Microfluidics Digital PCR for the Detection of KRAS Mutations.
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    Chapter 13 Negative Enrichment of Circulating Tumor Cells in Blood Using a Microfluidic Chip.
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    Chapter 14 Microfluidic-Based Bacteria Isolation from Whole Blood for Diagnostics of Blood Stream Infection.
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    Chapter 15 Microfluidic Platform for Parallel Single Cell Analysis for Diagnostic Applications.
  17. Altmetric Badge
    Chapter 16 FISH-in-CHIPS: A Microfluidic Platform for Molecular Typing of Cancer Cells.
Attention for Chapter 9: Droplet Microfluidic and Magnetic Particles Platform for Cancer Typing.
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Chapter title
Droplet Microfluidic and Magnetic Particles Platform for Cancer Typing.
Chapter number 9
Book title
Microchip Diagnostics
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6734-6_9
Pubmed ID
28044291
Book ISBNs
978-1-4939-6732-2, 978-1-4939-6734-6
Authors

Davide Ferraro, Jérôme Champ, Bruno Teste, M. Serra, Laurent Malaquin, Stéphanie Descroix, Patricia de Cremoux, Jean-Louis Viovy PhD, Jean-Louis Viovy

Editors

Valérie Taly, Jean-Louis Viovy, Stéphanie Descroix

Abstract

Analyses of nucleic acids are routinely performed in hospital laboratories to detect gene alterations for cancer diagnosis and treatment decision. Among the different possible investigations, mRNA analysis provides information on abnormal levels of genes expression. Standard laboratory methods are still not adapted to the isolation and quantitation of low mRNA amounts and new techniques needs to be developed in particular for rare subsets analysis. By reducing the volume involved, time process, and the contamination risks, droplet microfluidics provide numerous advantages to perform analysis down to the single cell level.We report on a droplet microfluidic platform based on the manipulation of magnetic particles that allows the clinical analysis of tumor tissues. In particular, it allows the extraction of mRNA from the total-RNA sample, Reverse Transcription, and cDNA amplification, all in droplets.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 21%
Student > Doctoral Student 2 14%
Researcher 2 14%
Professor 1 7%
Unspecified 1 7%
Other 2 14%
Unknown 3 21%
Readers by discipline Count As %
Physics and Astronomy 3 21%
Biochemistry, Genetics and Molecular Biology 2 14%
Agricultural and Biological Sciences 2 14%
Chemical Engineering 1 7%
Unspecified 1 7%
Other 2 14%
Unknown 3 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 January 2017.
All research outputs
#18,510,888
of 22,931,367 outputs
Outputs from Methods in molecular biology
#7,929
of 13,127 outputs
Outputs of similar age
#310,860
of 420,713 outputs
Outputs of similar age from Methods in molecular biology
#692
of 1,074 outputs
Altmetric has tracked 22,931,367 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,127 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 420,713 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,074 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.

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