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Mendeley readers
| Chapter title |
Patient-Derived Xenografts of Breast Cancer.
|
|---|---|
| Chapter number | 17 |
| Book title |
Mammary Gland Development
|
| Published in |
Methods in molecular biology, January 2017
|
| DOI | 10.1007/978-1-4939-6475-8_17 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-6473-4, 978-1-4939-6475-8
|
| Authors |
Damir Varešlija, Sinead Cocchiglia, Christopher Byrne, Leonie Young |
| Editors |
Finian Martin, Torsten Stein, Jillian Howlin |
| Abstract |
With the advancement of translational research, particularly in the field of cancer, it is now imperative to have models which more clearly reflect patient heterogeneity. Patient derived xenograft (PDX) models, which involve the orthotopic implantation of breast tumors into immune-compromised mice, recapitulate the native tumor biology. Despite the considerable challenges that establishing PDX models present, they are the ultimate model to study tumorigenesis of refractory disease and for assessing the efficacy of new pharmaceutical compounds. |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 5 | 29% |
| Student > Master | 2 | 12% |
| Researcher | 2 | 12% |
| Student > Bachelor | 2 | 12% |
| Unspecified | 1 | 6% |
| Other | 2 | 12% |
| Unknown | 3 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 47% |
| Biochemistry, Genetics and Molecular Biology | 2 | 12% |
| Agricultural and Biological Sciences | 1 | 6% |
| Unspecified | 1 | 6% |
| Physics and Astronomy | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 3 | 18% |