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Chromosome Architecture

Overview of attention for book
Attention for Chapter 11: DNA–Protein Interactions Studied Directly Using Single Molecule Fluorescence Imaging of Quantum Dot Tagged Proteins Moving on DNA Tightropes
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

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Chapter title
DNA–Protein Interactions Studied Directly Using Single Molecule Fluorescence Imaging of Quantum Dot Tagged Proteins Moving on DNA Tightropes
Chapter number 11
Book title
Chromosome Architecture
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3631-1_11
Pubmed ID
Book ISBNs
978-1-4939-3629-8, 978-1-4939-3631-1
Authors

Springall, Luke, Inchingolo, Alessio V., Kad, Neil M., Luke Springall, Alessio V. Inchingolo, Neil M. Kad

Editors

Mark C. Leake

Abstract

Many protein interactions with DNA require specific sequences; however, how these sequences are located remains uncertain. DNA normally appears bundled in solution but, to study DNA-protein interactions, the DNA needs to be elongated. Using fluidics single DNA strands can be efficiently and rapidly elongated between beads immobilized on a microscope slide surface. Such "DNA tightropes" offer a valuable method to study protein search mechanisms. Real-time fluorescence imaging of these interactions provides quantitative descriptions of search mechanism at the single molecule level. In our lab, we use this method to study the complex process of nucleotide excision DNA repair to determine mechanisms of damage detection, lesion removal, and DNA excision.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 40%
Student > Bachelor 3 30%
Lecturer 1 10%
Student > Master 1 10%
Unknown 1 10%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 40%
Agricultural and Biological Sciences 4 40%
Neuroscience 1 10%
Unknown 1 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 October 2016.
All research outputs
#8,544,290
of 25,396,120 outputs
Outputs from Methods in molecular biology
#2,644
of 14,177 outputs
Outputs of similar age
#127,440
of 399,795 outputs
Outputs of similar age from Methods in molecular biology
#277
of 1,465 outputs
Altmetric has tracked 25,396,120 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,177 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 399,795 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 1,465 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.