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New Psychoactive Substances

Overview of attention for book
Cover of 'New Psychoactive Substances'

Table of Contents

  1. Altmetric Badge
    Book Overview
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    Chapter 83 Bioanalytical Methods for New Psychoactive Substances
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    Chapter 102 Toxicokinetics of NPS: Update 2017
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    Chapter 107 Serotonergic Psychedelics: Experimental Approaches for Assessing Mechanisms of Action
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    Chapter 110 Fatal Poisonings Associated with New Psychoactive Substances
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    Chapter 111 Wastewater Analysis for Community-Wide Drugs Use Assessment
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    Chapter 113 Pharmacology of MDMA- and Amphetamine-Like New Psychoactive Substances
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    Chapter 124 Phencyclidine-Based New Psychoactive Substances
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    Chapter 127 Emergence, Diversity, and Control of New Psychoactive Substances: A Global Perspective
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    Chapter 134 Epidemiology of NPS Based Confirmed Overdose Cases: The STRIDA Project
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    Chapter 135 Patterns of Acute Toxicity Associated with New Psychoactive Substances
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    Chapter 143 The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonists as New Psychoactive Substances: Origins
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    Chapter 144 The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonist New Psychoactive Substances: Evolution
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    Chapter 148 1,2-Diarylethylamine- and Ketamine-Based New Psychoactive Substances
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    Chapter 149 Synthetic Opioids
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    Chapter 154 Designer Benzodiazepines: Another Class of New Psychoactive Substances
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    Chapter 160 Responding to New Psychoactive Substances in the European Union: Early Warning, Risk Assessment, and Control Measures
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    Chapter 177 Self-Experiments with Psychoactive Substances: A Historical Perspective
  19. Altmetric Badge
    Chapter 178 Neuropharmacology of Synthetic Cathinones
Attention for Chapter 144: The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonist New Psychoactive Substances: Evolution
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)

Mentioned by

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14 tweeters
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3 Wikipedia pages

Citations

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13 Dimensions

Readers on

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23 Mendeley
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Chapter title
The Chemistry and Pharmacology of Synthetic Cannabinoid Receptor Agonist New Psychoactive Substances: Evolution
Chapter number 144
Book title
Handbook of Experimental Pharmacology
Published in
Handbook of experimental pharmacology, August 2018
DOI 10.1007/164_2018_144
Pubmed ID
Book ISBNs
978-3-03-010560-0, 978-3-03-010561-7
Authors

Samuel D. Banister, Mark Connor, Banister, Samuel D., Connor, Mark

Abstract

Synthetic cannabinoid receptor agonists (SCRAs) are the largest and most structurally diverse class of new psychoactive substances (NPS). Although the earliest SCRA NPS were simply repurposed from historical academic manuscripts or pharmaceutical patents describing cannabinoid ligands, recent examples bear hallmarks of rational design. SCRA NPS manufacturers have applied traditional medicinal chemistry strategies (such as molecular hybridization, bioisosteric replacement, and scaffold hopping) to existing cannabinoid templates in order to generate new molecules that circumvent structure-based legislation. Most SCRAs potently activate cannabinoid type 1 and type 2 receptors (CB1 and CB2, respectively), with the former contributing to the psychoactivity of these substances. SCRAs are generally more toxic than the Δ9-tetrahydrocannabinol (Δ9-THC) found in cannabis, and this may be due to ligand bias, metabolism, or off-target activity. This chapter will chart the evolution of recently identified SCRA NPS chemotypes, as well as their putative manufacturing by-products and thermolytic degradants, and describe structure-activity relationships within each class.

Twitter Demographics

The data shown below were collected from the profiles of 14 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 30%
Student > Bachelor 4 17%
Student > Ph. D. Student 3 13%
Other 2 9%
Student > Doctoral Student 2 9%
Other 2 9%
Unknown 3 13%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 10 43%
Biochemistry, Genetics and Molecular Biology 4 17%
Chemistry 2 9%
Medicine and Dentistry 2 9%
Agricultural and Biological Sciences 1 4%
Other 0 0%
Unknown 4 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2022.
All research outputs
#2,370,896
of 22,601,066 outputs
Outputs from Handbook of experimental pharmacology
#84
of 642 outputs
Outputs of similar age
#48,313
of 300,763 outputs
Outputs of similar age from Handbook of experimental pharmacology
#1
of 1 outputs
Altmetric has tracked 22,601,066 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 642 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,763 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them