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TALENs

Overview of attention for book
Cover of 'TALENs'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 TALENs
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    Chapter 2 TAL Effector DNA-Binding Principles and Specificity.
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    Chapter 3 The Development of TALE Nucleases for Biotechnology.
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    Chapter 4 Online Tools for TALEN Design
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    Chapter 5 Assembly of Customized TAL Effectors Through Advanced ULtiMATE System
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    Chapter 6 Engineering Customized TALENs Using the Platinum Gate TALEN Kit
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    Chapter 7 Design, Assembly, and Characterization of TALE-Based Transcriptional Activators and Repressors.
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    Chapter 8 A New Approach to Dissect Nuclear Organization: TALE-Mediated Genome Visualization (TGV).
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    Chapter 9 TALEN-Induced Translocations in Human Cells
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    Chapter 10 Mutagenesis in Newts: Protocol for Iberian Ribbed Newts
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    Chapter 11 TALENs
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    Chapter 12 GeneKnockout by Targeted Mutagenesis in a Hemimetabolous Insect, the Two-Spotted Cricket Gryllus bimaculatus , using TALENs
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    Chapter 13 Methods for TALEN Evaluation, Use, and Mutation Detection in the Mosquito Aedes aegypti
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    Chapter 14 Methods for TALEN-Mediated Genomic Manipulations in Drosophila.
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    Chapter 15 Targeted Mutagenesis in Zebrafish by TALENs
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    Chapter 16 Mutagenesis in Xenopus and Zebrafish using TALENs
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    Chapter 17 Genome Editing in Mice Using TALE Nucleases.
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    Chapter 18 Genome Editing in Rats Using TALE Nucleases
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    Chapter 19 Designer Nuclease-Mediated Generation of Knockout THP1 Cells
Attention for Chapter 9: TALEN-Induced Translocations in Human Cells
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

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Citations

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Chapter title
TALEN-Induced Translocations in Human Cells
Chapter number 9
Book title
TALENs
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-2932-0_9
Pubmed ID
Book ISBNs
978-1-4939-2931-3, 978-1-4939-2932-0
Authors

Marion Piganeau, Benjamin Renouf, Hind Ghezraoui, Erika Brunet, Piganeau, Marion, Renouf, Benjamin, Ghezraoui, Hind, Brunet, Erika

Abstract

Induction of chromosomal translocations in human cells is of a great interest to study tumorigenesis and genome instability. Here, we explain in detail a method to induce translocations using the transcription activator-like effector nucleases (TALENs). We describe how to detect translocation formation by PCR, calculate translocation frequency by 96-well PCR screen, and analyze breakpoint junctions. When inducing cancer translocations, it is also possible to detect the fusion gene by FISH analysis or western blot.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 4 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 4 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 50%
Researcher 2 50%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 25%
Agricultural and Biological Sciences 1 25%
Physics and Astronomy 1 25%
Materials Science 1 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2020.
All research outputs
#4,229,935
of 23,045,021 outputs
Outputs from Methods in molecular biology
#1,137
of 13,194 outputs
Outputs of similar age
#72,223
of 394,759 outputs
Outputs of similar age from Methods in molecular biology
#168
of 1,471 outputs
Altmetric has tracked 23,045,021 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,194 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,759 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 1,471 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.