| Chapter title |
Derivation of Neural Stem Cells from the Developing and Adult Human Brain
|
|---|---|
| Chapter number | 1 |
| Book title |
Human Neural Stem Cells
|
| Published in |
Results and problems in cell differentiation, January 2018
|
| DOI | 10.1007/978-3-319-93485-3_1 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-993484-6, 978-3-31-993485-3
|
| Authors |
Claire M. Kelly, Maeve A. Caldwell, Kelly, Claire M., Caldwell, Maeve A. |
| Abstract |
Neural stem cells isolated from the developing and adult brain are an ideal source of cells for use in clinical applications such as cell replacement therapy. The clear advantage of these cells over the more commonly utilised embryonic and pluripotent stem cells is that they are already neurally committed. Of particular importance is the fact that these cells don't require the same level of in vitro culture that can be cost and labour intensive. Foetal neural stem cells can be readily derived from the foetal brain and expand in culture over time. Similarly, adult stem cells have been explored for their potential in vitro and in vivo animal models. In this chapter we identify the progress made in developing these cells as well as the advantages of taking them forward for clinical use. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 5 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 1 | 20% |
| Professor > Associate Professor | 1 | 20% |
| Student > Bachelor | 1 | 20% |
| Student > Master | 1 | 20% |
| Unknown | 1 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 3 | 60% |
| Medicine and Dentistry | 1 | 20% |
| Unknown | 1 | 20% |