| Chapter title |
Methylation and MicroRNA Profiling to Understand Racial Disparities of Prostate Cancer
|
|---|---|
| Chapter number | 15 |
| Book title |
Cancer Epigenetics for Precision Medicine
|
| Published in |
Methods in molecular biology, September 2018
|
| DOI | 10.1007/978-1-4939-8751-1_15 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-8750-4, 978-1-4939-8751-1
|
| Authors |
Hirendra Nath Banerjee, William Kahan, Vineet Kumar, Mukesh Verma |
| Abstract |
Prostate cancer is a serious disease in terms of its high incidence and mortality rate in the USA and around the world. The prostate specific antigen (PSA) has been used for prostate cancer diagnosis and follow-up of treatment but a number of challenges remain. Epigenetic biomarkers, especially methylation and microRNA (miR) biomarkers provide an opportunity for diagnosis, prognosis, and recurrence of prostate cancer. Differential global methylation has shown some promising results. In this chapter, the emphasis is given on those biomarkers which can be assayed noninvasively in a prospective study and in a clinic. Challenges in the field, especially the validation of potential biomarkers, and their potential solutions are provided in this chapter. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 5 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 3 | 60% |
| Student > Bachelor | 1 | 20% |
| Other | 1 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 2 | 40% |
| Nursing and Health Professions | 1 | 20% |
| Biochemistry, Genetics and Molecular Biology | 1 | 20% |
| Unknown | 1 | 20% |