↓ Skip to main content
What is this page? Embed badge

Cancer Epigenetics for Precision Medicine

Overview of attention for book
Cover of 'Cancer Epigenetics for Precision Medicine'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Early Epigenetic Markers for Precision Medicine
  3. Altmetric Badge
    Chapter 2 Interplay Between Genetic and Epigenetic Changes in Breast Cancer Subtypes
  4. Altmetric Badge
    Chapter 3 Role of Microbiome in Carcinogenesis Process and Epigenetic Regulation of Colorectal Cancer
  5. Altmetric Badge
    Chapter 4 Epigenome-Based Precision Medicine in Lung Cancer
  6. Altmetric Badge
    Chapter 4 Review on Current Trends of Deep Learning
  7. Altmetric Badge
    Chapter 5 Epigenetics in Hematological Malignancies
  8. Altmetric Badge
    Chapter 6 MicroRNAs Role in Prostate Cancer
  9. Altmetric Badge
    Chapter 7 Effects of Dietary Nutrients on Epigenetic Changes in Cancer
  10. Altmetric Badge
    Chapter 8 Diet, Microbiome, and Epigenetics in the Era of Precision Medicine
  11. Altmetric Badge
    Chapter 9 Alcohol-Induced Epigenetic Changes in Cancer
  12. Altmetric Badge
    Chapter 10 Epigenetic Basis of Circadian Rhythm Disruption in Cancer
  13. Altmetric Badge
    Chapter 11 Epigenetic Changes of the Immune System with Role in Tumor Development
  14. Altmetric Badge
    Chapter 12 DNA Methylation as a Biomarker of Aging in Epidemiologic Studies
  15. Altmetric Badge
    Chapter 13 Challenges and Opportunities in Social Epigenomics and Cancer
  16. Altmetric Badge
    Chapter 14 Epigenetic and Genetic Regulation of PDCD1 Gene in Cancer Immunology
  17. Altmetric Badge
    Chapter 15 Methylation and MicroRNA Profiling to Understand Racial Disparities of Prostate Cancer
  18. Altmetric Badge
    Chapter 16 Analysis of DNA Hypermethylation in Pancreatic Cancer Using Methylation-Specific PCR and Bisulfite Sequencing
  19. Altmetric Badge
    Chapter 17 Pyrosequencing Methylation Analysis
Attention for Chapter 14: Epigenetic and Genetic Regulation of PDCD1 Gene in Cancer Immunology
Altmetric Badge

Mentioned by

twitter
2 X users

Citations

dimensions_citation
1 Dimensions

Readers on

mendeley
24 Mendeley
Summary X Dimensions citations
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Chapter title
Epigenetic and Genetic Regulation of PDCD1 Gene in Cancer Immunology
Chapter number 14
Book title
Cancer Epigenetics for Precision Medicine
Published in
Methods in molecular biology, September 2018
DOI 10.1007/978-1-4939-8751-1_14
Pubmed ID
30178256
Book ISBNs
978-1-4939-8750-4, 978-1-4939-8751-1
Authors

Alok Mishra, Mukesh Verma

Abstract

Utilizing biology of PD-1: PD-L1 interaction related pathways for cancer immunotherapy is an emerging concept in cancer research. However, there is limited literature on epigenetic regulation of PD1 gene (PDCD1). Promising data from clinical trials of PD/PDl-1 immunotherapy in melanoma, renal cancers, colorectal and lung cancers has generated a lot of hope for successful treatment of patients. Immunotherapy in cancers has a significant role in strategizing NCI's Cancer Moonshot Program of US NIH and FDA policies. The cost of the treatment by immunotherapy is extremely high. This preview presents a concise compilation of current knowledge on how the PD-1 gene is regulated in different cancers and infections. We have also discussed about epigenetic regulation of PDCD1 gene, especially the effect of different epigenetic inhibitors of DNA methylation and histone modifications at different steps in PD-1 regulation.

View on publisher site
X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 17%
Student > Master 4 17%
Student > Ph. D. Student 4 17%
Student > Postgraduate 3 13%
Student > Doctoral Student 1 4%
Other 3 13%
Unknown 5 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 29%
Medicine and Dentistry 5 21%
Agricultural and Biological Sciences 2 8%
Immunology and Microbiology 1 4%
Economics, Econometrics and Finance 1 4%
Other 1 4%
Unknown 7 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2018.
All research outputs
#19,323,874
of 23,923,788 outputs
Outputs from Methods in molecular biology
#8,297
of 13,508 outputs
Outputs of similar age
#261,984
of 338,120 outputs
Outputs of similar age from Methods in molecular biology
#162
of 249 outputs
Altmetric has tracked 23,923,788 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,508 research outputs from this source. They receive a mean Attention Score of 3.5. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 338,120 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 249 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.

This page is provided by Altmetric.