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Molecular Mechanisms of Notch Signaling

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Attention for Chapter 17: Notch and T Cell Function – A Complex Tale
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Chapter title
Notch and T Cell Function – A Complex Tale
Chapter number 17
Book title
Molecular Mechanisms of Notch Signaling
Published in
Advances in experimental medicine and biology, January 2018
DOI 10.1007/978-3-319-89512-3_17
Pubmed ID
Book ISBNs
978-3-31-989511-6, 978-3-31-989512-3
Authors

Jyothi Vijayaraghavan, Barbara A. Osborne, Vijayaraghavan, Jyothi, Osborne, Barbara A.

Abstract

Notch drives critical decisions in a multitude of developmental decisions in many invertebrate and vertebrate organisms including flies, worms, fish, mice and humans. Therefore, it is not surprising that Notch family members also play a key role in cell fate choices in the vertebrate immune system. This review highlights the critical function of Notch in the development of mature T lymphocytes from hematopoietic precursors and describes the role of Notch in mature T cell activation, proliferation and differentiation.

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Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 31%
Researcher 3 23%
Student > Bachelor 1 8%
Professor 1 8%
Student > Doctoral Student 1 8%
Other 0 0%
Unknown 3 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 46%
Immunology and Microbiology 2 15%
Agricultural and Biological Sciences 1 8%
Nursing and Health Professions 1 8%
Unknown 3 23%