Chapter title |
Intracerebral Hemorrhage in Mice
|
---|---|
Chapter number | 7 |
Book title |
Traumatic and Ischemic Injury
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7526-6_7 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7524-2, 978-1-4939-7526-6
|
Authors |
Damon Klebe, Loretta Iniaghe, Sherrefa Burchell, Cesar Reis, Onat Akyol, Jiping Tang, John H. Zhang |
Abstract |
Intracerebral hemorrhage is the most devastating stroke subtype with high rates of mortality and morbidity. Furthermore, no clinically approved treatment exists that effectively increases survival or improves quality of life for survivors. Effective modeling is necessary to elucidate the pathophysiological mechanisms of intracerebral hemorrhage and evaluate potential therapeutic approaches. Rodent models are most utilized because of their cost-effectiveness, and because rodent brain development and structures are well documented. Herein, we describe two intracerebral hemorrhage mouse models: the autologous blood double-injection and collagenase infusion models. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 3 | 14% |
Student > Doctoral Student | 3 | 14% |
Student > Master | 3 | 14% |
Researcher | 2 | 9% |
Student > Ph. D. Student | 1 | 5% |
Other | 3 | 14% |
Unknown | 7 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 23% |
Neuroscience | 4 | 18% |
Biochemistry, Genetics and Molecular Biology | 3 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Veterinary Science and Veterinary Medicine | 1 | 5% |
Other | 0 | 0% |
Unknown | 8 | 36% |