Chapter title |
Nutritional Programming Effects on the Immune System
|
---|---|
Chapter number | 20 |
Book title |
Investigations of Early Nutrition Effects on Long-Term Health
|
Published in |
Methods in molecular biology, January 2018
|
DOI | 10.1007/978-1-4939-7614-0_20 |
Pubmed ID | |
Book ISBNs |
978-1-4939-7613-3, 978-1-4939-7614-0
|
Authors |
Donald B. Palmer |
Abstract |
The relationship between patterns of early growth and age-associated diseases such as type 2 diabetes and cardiovascular disease is well established. There is also strong evidence from both human and animal studies that early environmental factors such as maternal nutrition may influence lifespan. Interestingly, more recent studies have demonstrated that nutritional programming in early life effects immunity, such that altered lifespan can also lead to programmed changes in immune function. Here we describe the use of immunohistology and flow cytometry techniques to study two key immune lymphoid organs: one that is involved in developing immune cells (thymus) and another which is the site of immune activation (spleen). |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 6 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Unspecified | 1 | 17% |
Student > Ph. D. Student | 1 | 17% |
Student > Bachelor | 1 | 17% |
Other | 1 | 17% |
Student > Master | 1 | 17% |
Other | 0 | 0% |
Unknown | 1 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 2 | 33% |
Unspecified | 1 | 17% |
Immunology and Microbiology | 1 | 17% |
Medicine and Dentistry | 1 | 17% |
Unknown | 1 | 17% |