| Chapter title |
Exosomes in Tumor Angiogenesis
|
|---|---|
| Chapter number | 3 |
| Book title |
Tumor Angiogenesis Assays
|
| Published in |
Methods in molecular biology, January 2016
|
| DOI | 10.1007/978-1-4939-3999-2_3 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-3997-8, 978-1-4939-3999-2
|
| Authors |
Karma Z. Salem, Michele Moschetta, Antonio Sacco, Luisa Imberti, Giuseppe Rossi, Irene M. Ghobrial, Salomon Manier, Aldo M. Roccaro |
| Abstract |
Exosomes are small vesicles ranging in size between 30 and 150 nm, derived from the luminal membranes of the endosome and are constitutively released by fusion with the cell membrane. Several studies have revealed that exosomes play crucial roles in mediating local and systemic cell communication through the horizontal transfer of information in the form of nucleic material and proteins. This is particularly relevant in the context of the tumor-microenvironment cross talk. Here we describe the method of isolating exosomes and their role in modifying the tumor environment and more specifically in enabling metastasis and promoting angiogenesis. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 65 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 20% |
| Researcher | 7 | 11% |
| Student > Master | 6 | 9% |
| Student > Doctoral Student | 4 | 6% |
| Student > Bachelor | 4 | 6% |
| Other | 5 | 8% |
| Unknown | 26 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 14 | 22% |
| Agricultural and Biological Sciences | 6 | 9% |
| Medicine and Dentistry | 4 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Engineering | 2 | 3% |
| Other | 6 | 9% |
| Unknown | 30 | 46% |