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Tumor Angiogenesis Assays

Overview of attention for book
Attention for Chapter 8: An Ex Vivo Tissue Culture Model for Anti-angiogenic Drug Testing
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Chapter title
An Ex Vivo Tissue Culture Model for Anti-angiogenic Drug Testing
Chapter number 8
Book title
Tumor Angiogenesis Assays
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3999-2_8
Pubmed ID
Book ISBNs
978-1-4939-3997-8, 978-1-4939-3999-2
Authors

Mohammad S. Azimi, Michelle Lacey, Debasis Mondal, Walter L. Murfee

Abstract

Angiogenesis, defined as the growth of new blood vessels from existing ones, plays a key role in development, growth, and tissue repair. Its necessary role in tumor growth and metastasis has led to the creation of a new category of anti-angiogenic cancer therapies. Preclinical development and evaluation of potential drug candidates require models that mimic real microvascular networks. Here, we describe the rat mesentery culture model as a simple ex vivo assay that offers time-lapse imaging of intact microvascular network remodeling and demonstrate its application for anti-angiogenic drug testing.

X Demographics

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 29%
Student > Bachelor 2 29%
Professor > Associate Professor 1 14%
Professor 1 14%
Unknown 1 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 2 29%
Chemistry 1 14%
Medicine and Dentistry 1 14%
Engineering 1 14%
Unknown 2 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 January 2018.
All research outputs
#15,488,947
of 23,016,919 outputs
Outputs from Methods in molecular biology
#5,388
of 13,165 outputs
Outputs of similar age
#232,206
of 394,704 outputs
Outputs of similar age from Methods in molecular biology
#546
of 1,471 outputs
Altmetric has tracked 23,016,919 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,165 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,704 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,471 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.