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X Demographics
Mendeley readers
Attention Score in Context
| Chapter title |
Chemical Genomic Profiling via Barcode Sequencing to Predict Compound Mode of Action.
|
|---|---|
| Chapter number | 23 |
| Book title |
Chemical Biology
|
| Published in |
Methods in molecular biology, January 2015
|
| DOI | 10.1007/978-1-4939-2269-7_23 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-2268-0, 978-1-4939-2269-7
|
| Authors |
Jeff S Piotrowski, Scott W Simpkins, Sheena C Li, Raamesh Deshpande, Sean J McIlwain, Irene M Ong, Chad L Myers, Charlie Boone, Raymond J Andersen, Jeff S. Piotrowski, Scott W. Simpkins, Sheena C. Li, Sean J. McIlwain, Irene M. Ong, Chad L. Myers, Raymond J. Andersen |
| Abstract |
Chemical genomics is an unbiased, whole-cell approach to characterizing novel compounds to determine mode of action and cellular target. Our version of this technique is built upon barcoded deletion mutants of Saccharomyces cerevisiae and has been adapted to a high-throughput methodology using next-generation sequencing. Here we describe the steps to generate a chemical genomic profile from a compound of interest, and how to use this information to predict molecular mechanism and targets of bioactive compounds. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| France | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| Indonesia | 1 | 2% |
| Italy | 1 | 2% |
| Unknown | 54 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 17 | 29% |
| Student > Ph. D. Student | 9 | 16% |
| Student > Master | 5 | 9% |
| Student > Doctoral Student | 4 | 7% |
| Student > Postgraduate | 4 | 7% |
| Other | 13 | 22% |
| Unknown | 6 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 18 | 31% |
| Agricultural and Biological Sciences | 16 | 28% |
| Computer Science | 4 | 7% |
| Chemistry | 4 | 7% |
| Immunology and Microbiology | 3 | 5% |
| Other | 4 | 7% |
| Unknown | 9 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 January 2015.
All research outputs
#14,191,062
of 23,198,445 outputs
Outputs from Methods in molecular biology
#4,009
of 13,301 outputs
Outputs of similar age
#183,495
of 354,966 outputs
Outputs of similar age from Methods in molecular biology
#255
of 1,002 outputs
Altmetric has tracked 23,198,445 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,301 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,966 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1,002 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.