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Innate Immune Activation

Overview of attention for book
Cover of 'Innate Immune Activation'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 1 Emerging Concepts in Innate Immunity
  3. Altmetric Badge
    Chapter 2 Bioinformatic Assessment of Macrophage Activation by the Innate Immune System
  4. Altmetric Badge
    Chapter 3 Generation of Genetic Knockouts in Myeloid Cell Lines Using a Lentiviral CRISPR/Cas9 System
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    Chapter 4 Modeling Primary Human Monocytes with the Trans–Differentiation Cell Line BLaER1
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    Chapter 5 Measurement of NF-κB Activation in TLR-Activated Macrophages
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    Chapter 6 Biochemical Isolation of the Myddosome from Murine Macrophages
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    Chapter 7 Generation of Innate Immune Reporter Cells Using Retroviral Transduction
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    Chapter 8 Examining Myddosome Formation by Luminescence-Based Mammalian Interactome Mapping (LUMIER)
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    Chapter 9 Inflammatory Caspases: Activation and Cleavage of Gasdermin-D In Vitro and During Pyroptosis
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    Chapter 10 Detection of ASC Speck Formation by Flow Cytometry and Chemical Cross-linking
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    Chapter 11 Measuring Innate Immune Responses to Bacterial Viability
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    Chapter 12 Methods to Study Cell Swelling-Induced Inflammasome Activation
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    Chapter 13 Detecting Release of Bacterial dsDNA into the Host Cytosol Using Fluorescence Microscopy
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    Chapter 14 Quantitative Proteomics of Secreted Proteins
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    Chapter 15 Simultaneous Detection of Cellular Viability and Interleukin-1β Secretion from Single Cells by ELISpot
  17. Altmetric Badge
    Chapter 16 Detection and Quantification of MAVS Aggregation via Confocal Microscopy
Attention for Chapter 2: Bioinformatic Assessment of Macrophage Activation by the Innate Immune System
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (55th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

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Citations

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Chapter title
Bioinformatic Assessment of Macrophage Activation by the Innate Immune System
Chapter number 2
Book title
Innate Immune Activation
Published in
Methods in molecular biology, January 2018
DOI 10.1007/978-1-4939-7519-8_2
Pubmed ID
Book ISBNs
978-1-4939-7518-1, 978-1-4939-7519-8
Authors

Thomas Ulas, Joachim L. Schultze, Marc Beyer

Abstract

Weighted gene co-expression network analysis (WGCNA) allows for the identification and characterization of cell type-specific gene modules in complex transcriptome datasets. Here, we use a microarray dataset of human macrophages comprising 29 conditions and 299 samples generated by differentiation of CD14+ monocytes into macrophages followed by in vitro stimulations to identify stimulation-specific gene modules. These gene modules can be used for experimental validation, as well as further bioinformatic analysis to determine key pathways or upstream transcription factors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 2 25%
Student > Bachelor 2 25%
Researcher 2 25%
Student > Doctoral Student 1 13%
Unknown 1 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 38%
Biochemistry, Genetics and Molecular Biology 2 25%
Immunology and Microbiology 1 13%
Neuroscience 1 13%
Unknown 1 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2018.
All research outputs
#7,541,834
of 23,009,818 outputs
Outputs from Methods in molecular biology
#2,339
of 13,157 outputs
Outputs of similar age
#153,693
of 442,295 outputs
Outputs of similar age from Methods in molecular biology
#230
of 1,498 outputs
Altmetric has tracked 23,009,818 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,157 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 442,295 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 1,498 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.