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Mendeley readers
| Chapter title |
Detection and Quantification of MAVS Aggregation via Confocal Microscopy
|
|---|---|
| Chapter number | 16 |
| Book title |
Innate Immune Activation
|
| Published in |
Methods in molecular biology, January 2018
|
| DOI | 10.1007/978-1-4939-7519-8_16 |
| Pubmed ID | |
| Book ISBNs |
978-1-4939-7518-1, 978-1-4939-7519-8
|
| Authors |
Tan A. Nguyen, Lachlan Whitehead, Ken C. Pang |
| Abstract |
During infection, the cytosolic detection of viral double-stranded RNA (dsRNA) leads to the oligomerization and activation of mitochondrial antiviral signaling protein (MAVS) and the subsequent production of type I interferon (IFN). Here, we describe a novel method of visualizing and quantifying the aggregation of MAVS in response to dsRNA stimulation or viral infection in vitro using confocal microscopy. |
Mendeley readers
The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 7 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 3 | 43% |
| Researcher | 2 | 29% |
| Professor > Associate Professor | 1 | 14% |
| Unknown | 1 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 4 | 57% |
| Biochemistry, Genetics and Molecular Biology | 2 | 29% |
| Unknown | 1 | 14% |