| Chapter title |
The Future of Atopic Dermatitis Treatment
|
|---|---|
| Chapter number | 15 |
| Book title |
Management of Atopic Dermatitis
|
| Published in |
Advances in experimental medicine and biology, January 2017
|
| DOI | 10.1007/978-3-319-64804-0_15 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-964803-3, 978-3-31-964804-0
|
| Authors |
Nupur Patel, Lindsay C. Strowd |
| Abstract |
In recent years, there has been a growing movement towards the use of targeted therapies in treating of atopic dermatitis (AD), parallel to that which has occurred in psoriasis. Among the systemic medications being studied are subcutaneous or intravenously administered biologic drugs targeting specific molecules such as IL4, IL13, IL17, and IgE. Non-biologic oral therapies are also being developed for AD and include small molecule drugs targeting phosphodiesterase type IV (PDE4) inhibition or Janus Kinase (JAK) inhibition. Numerous topical formulations are also being studied, with some formulations that are novel therapies that act as topical biologic or small molecule agents with mechanisms of action similar to systemic treatments. Others are being developed as skin barrier repair therapies for reduction of AD symptoms. This chapter will discuss new advances in AD treatment from medications in the initial stages of development to those nearing FDA approval. |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 29 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 17% |
| Student > Master | 3 | 10% |
| Other | 2 | 7% |
| Student > Ph. D. Student | 1 | 3% |
| Professor | 1 | 3% |
| Other | 2 | 7% |
| Unknown | 15 | 52% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 14% |
| Biochemistry, Genetics and Molecular Biology | 2 | 7% |
| Veterinary Science and Veterinary Medicine | 1 | 3% |
| Computer Science | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 14 | 48% |