Chapter title |
Sex-Related Differences in GI Disorders
|
---|---|
Chapter number | 121 |
Book title |
Gastrointestinal Pharmacology
|
Published in |
Handbook of experimental pharmacology, January 2017
|
DOI | 10.1007/164_2016_121 |
Pubmed ID | |
Book ISBNs |
978-3-31-956359-6, 978-3-31-956360-2
|
Authors |
Dawn K. Prusator, Lin Chang, Prusator, Dawn K., Chang, Lin |
Abstract |
Epidemiological studies indicate sex-related differences among functional gastrointestinal disorders (FGIDs) wherein females are more likely to receive a diagnosis than their male counterparts. However, the mechanism by which females exhibit an increased vulnerability for development of these pathophysiologies remains largely unknown, and therapeutic treatments are limited. The current chapter focuses on clinical research outlining our current knowledge of factors that contribute to the female predominance among FGID patients such as the menstrual cycle and sex hormones. In addition, we will discuss progress in preclinical research, including animal models, which serve as valuable tools for the investigation of the development and long term manifestation of symptoms observed within the patient population. Although much progress has been made, additional longitudinal studies in both clinical and preclinical research are necessary to identify more specific mechanisms underlying sex-related differences in FGIDs as well as targets for improved therapeutic approaches. |
X Demographics
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 46 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 13% |
Student > Ph. D. Student | 5 | 11% |
Researcher | 4 | 9% |
Other | 4 | 9% |
Professor | 3 | 7% |
Other | 10 | 22% |
Unknown | 14 | 30% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 24% |
Psychology | 4 | 9% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Agricultural and Biological Sciences | 3 | 7% |
Nursing and Health Professions | 1 | 2% |
Other | 5 | 11% |
Unknown | 19 | 41% |