Chapter title |
Inflammatory Bowel Disease: Pathophysiology and Current Therapeutic Approaches
|
---|---|
Chapter number | 122 |
Book title |
Gastrointestinal Pharmacology
|
Published in |
Handbook of experimental pharmacology, February 2017
|
DOI | 10.1007/164_2016_122 |
Pubmed ID | |
Book ISBNs |
978-3-31-956359-6, 978-3-31-956360-2
|
Authors |
Bincy P. Abraham, Tasneem Ahmed, Tauseef Ali, Abraham, Bincy P., Ahmed, Tasneem, Ali, Tauseef |
Abstract |
Inflammatory bowel diseases, most commonly categorized as Crohn's disease and ulcerative colitis, are immune mediated chronic inflammatory disorders of the gastrointestinal tract. The etiopathogenesis is multifactorial with different environmental, genetic, immune mediated, and gut microbial factors playing important role. The current goals of therapy are to improve clinical symptoms, control inflammation, prevent complications, and improve quality of life. Different therapeutic agents, with their indications, mechanisms of action, and side effects are discussed in this chapter. Anti-integrin therapy, a newer therapeutic class, with its potential beneficial role in both Crohn's disease and ulcerative colitis is also mentioned. In the end, therapeutic algorithms for both diseases are reviewed. |
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Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 193 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 31 | 16% |
Student > Master | 14 | 7% |
Student > Doctoral Student | 13 | 7% |
Other | 12 | 6% |
Researcher | 12 | 6% |
Other | 24 | 12% |
Unknown | 87 | 45% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 43 | 22% |
Pharmacology, Toxicology and Pharmaceutical Science | 17 | 9% |
Biochemistry, Genetics and Molecular Biology | 10 | 5% |
Immunology and Microbiology | 7 | 4% |
Nursing and Health Professions | 6 | 3% |
Other | 18 | 9% |
Unknown | 92 | 48% |