Gastrointestinal Pharmacology
Springer, Cham
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X Demographics
Mendeley readers
Attention Score in Context
| Chapter title |
Cannabinoid Receptors in Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance
|
|---|---|
| Chapter number | 105 |
| Book title |
Gastrointestinal Pharmacology
|
| Published in |
Handbook of experimental pharmacology, February 2017
|
| DOI | 10.1007/164_2016_105 |
| Pubmed ID | |
| Book ISBNs |
978-3-31-956359-6, 978-3-31-956360-2
|
| Authors |
Taschler, Ulrike, Hasenoehrl, Carina, Storr, Martin, Schicho, Rudolf, Ulrike Taschler, Carina Hasenoehrl, Martin Storr, Rudolf Schicho |
| Abstract |
Cannabinoid receptors are fundamentally involved in all aspects of intestinal physiology, such as motility, secretion, and epithelial barrier function. They are part of a broader entity, the so-called endocannabinoid system which also includes their endocannabinoid ligands and the ligands' synthesizing/degrading enzymes. The system has a strong impact on the pathophysiology of the gastrointestinal tract and is believed to maintain homeostasis in the gut by controlling hypercontractility and by promoting regeneration after injury. For instance, genetic knockout of cannabinoid receptor 1 leads to inflammation and cancer of the intestines. Derivatives of Δ(9)-tetrahydrocannabinol, such as nabilone and dronabinol, activate cannabinoid receptors and have been introduced into the clinic to treat chemotherapy-induced emesis and loss of appetite; however, they may cause many psychotropic side effects. New drugs that interfere with endocannabinoid degradation to raise endocannabinoid levels circumvent this obstacle and could be used in the future to treat emesis, intestinal inflammation, and functional disorders associated with visceral hyperalgesia. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 25% |
| United States | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 52 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 8 | 15% |
| Student > Bachelor | 7 | 13% |
| Researcher | 6 | 12% |
| Student > Ph. D. Student | 6 | 12% |
| Student > Postgraduate | 4 | 8% |
| Other | 6 | 12% |
| Unknown | 15 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 10 | 19% |
| Biochemistry, Genetics and Molecular Biology | 7 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 10% |
| Agricultural and Biological Sciences | 4 | 8% |
| Neuroscience | 3 | 6% |
| Other | 7 | 13% |
| Unknown | 16 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2017.
All research outputs
#7,625,075
of 23,939,410 outputs
Outputs from Handbook of experimental pharmacology
#234
of 663 outputs
Outputs of similar age
#139,936
of 426,529 outputs
Outputs of similar age from Handbook of experimental pharmacology
#12
of 32 outputs
Altmetric has tracked 23,939,410 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 663 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.1. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 426,529 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.