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Macro-Glycoligands

Overview of attention for book
Cover of 'Macro-Glycoligands'

Table of Contents

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    Book Overview
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    Chapter 1 Synthesis of Chain-End Functionalized Glycopolymers via Cyanoxyl-Mediated Free Radical Polymerization (CMFRP)
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    Chapter 2 Protecting-Group-Free Synthesis of Well-Defined Glycopolymers Featuring Negatively Charged Oligosaccharides
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    Chapter 3 Glycopolymers Prepared by Ring-Opening Metathesis Polymerization Followed by Glycoconjugation Using a Triazole-Forming “Click” Reaction
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    Chapter 4 Protecting-Group-Free Synthesis of Glycopolymers and Their Binding Assay with Lectin and Influenza Virus
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    Chapter 5 Carbohydrate-Based Initiators for the Cationic Ring-Opening Polymerization of 2-Ethyl-2-Oxazoline
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    Chapter 6 Heterofunctional Glycopolypeptides by Combination of Thiol-Ene Chemistry and NCA Polymerization
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    Chapter 7 Preparation of Proteoglycan Mimetic Graft Copolymers
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    Chapter 8 Galactosylated Polymer Nano-objects by Polymerization-Induced Self-Assembly, Potential Drug Nanocarriers.
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    Chapter 9 Synthetic Approach to Biotinylated Glyco-Functionalized Quantum Dots: A New Fluorescent Probes for Biomedical Applications
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    Chapter 10 Surface Modification of Polydivinylbenzene Microspheres with a Fluorinated Glycopolymer Using Thiol-Halogen Click Chemistry
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    Chapter 11 Glycopolymer-Grafted Polymer Particles for Lectin Recognition
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    Chapter 12 Synthesis of Non-spherical Glycopolymer-Decorated Nanoparticles: Combing Thiol-ene with Catecholic Chemistry
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    Chapter 13 Synthetic Approach to Glycopolymer Base Nanoparticle Gold(I) Conjugate: A New Generation of Therapeutic Agents
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    Chapter 14 Multivalent Glycopolymer-Coated Gold Nanoparticles
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    Chapter 15 Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry
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    Chapter 16 Oriented Immobilized Sialyloligo-macroligand Microarray
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    Chapter 17 Glycocalyx Remodeling with Glycopolymer-Based Proteoglycan Mimetics
Attention for Chapter 14: Multivalent Glycopolymer-Coated Gold Nanoparticles
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Chapter title
Multivalent Glycopolymer-Coated Gold Nanoparticles
Chapter number 14
Book title
Macro-Glycoligands
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3130-9_14
Pubmed ID
Book ISBNs
978-1-4939-3129-3, 978-1-4939-3130-9
Authors

Sarah-Jane Richards, Caroline I. Biggs, Matthew I. Gibson

Abstract

Glycosylated noble metal nanoparticles are a useful tool for probing biological binding events due to their aggregation-induced color changes, particularly for lectins that have multiple binding sites. To overcome the challenges of colloidal instability, which leads to false-positive results, it is essential to add polymeric coatings to these particles. Here we describe a versatile, and reliable, approach to enable coating of gold nanoparticles using well-defined polymers, with carbohydrate end groups. This produces multivalent nanoparticles that are both colloidally stable, but still retain their rapid colorimetric responses to lectin binding.

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Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 40%
Researcher 2 40%
Professor > Associate Professor 1 20%
Readers by discipline Count As %
Chemistry 3 60%
Pharmacology, Toxicology and Pharmaceutical Science 1 20%
Unknown 1 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 September 2017.
All research outputs
#20,447,499
of 23,002,898 outputs
Outputs from Methods in molecular biology
#9,937
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Outputs of similar age
#331,742
of 394,604 outputs
Outputs of similar age from Methods in molecular biology
#1,054
of 1,471 outputs
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