Chapter title |
Galactosylated Polymer Nano-objects by Polymerization-Induced Self-Assembly, Potential Drug Nanocarriers.
|
---|---|
Chapter number | 8 |
Book title |
Macro-Glycoligands
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3130-9_8 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3129-3, 978-1-4939-3130-9
|
Authors |
Semsarilar, Mona, Canton, Irene, Ladmiral, Vincent, Mona Semsarilar, Irene Canton, Vincent Ladmiral |
Abstract |
Glycopolymer-based nanostructures are invaluable tools to both study biological phenomena and to design future targeted drug delivery systems. Polymerization-induced self-assembly, especially RAFT aqueous dispersion polymerization is a unique method to prepare such polymer nanostructures, as it enables the preparation of very-well-defined morphologies at very high concentrations. Here we describe the implementation of PISA to the synthesis of galactosylated spheres, wormlike micelles and vesicles, and the preliminary results of cell toxicity, cell uptake, and cargo delivering capacity of galactose-decorated vesicles. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 5 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 1 | 20% |
Researcher | 1 | 20% |
Lecturer | 1 | 20% |
Student > Master | 1 | 20% |
Unknown | 1 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 3 | 60% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 20% |
Unknown | 1 | 20% |