Chapter title |
Synthetic Approach to Biotinylated Glyco-Functionalized Quantum Dots: A New Fluorescent Probes for Biomedical Applications
|
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Chapter number | 9 |
Book title |
Macro-Glycoligands
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3130-9_9 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3129-3, 978-1-4939-3130-9
|
Authors |
Christian K. Adokoh, James Darkwa, Ravin Narain |
Abstract |
Technological advances that allow deeper penetration in live tissues, such as the development of confocal and the generation of ever-new fluorophores that facilitate bright labeling of cells and tissue components have made imaging of vertebrate model organisms efficient and highly informative. Recently, high luminescence, single-excitation narrow emission, low photo bleaching properties, and low toxicity of high-quality water-soluble QDs have attracted attention for in vivo labeling/imaging of cells. Herein we describe a synthetic approach to biotinylated glycopolymer functionalized quantum dots, with special emphasis on the development of high-quality water-soluble and bioactive QDs with low toxicity for fluorescent probes in biomedical applications. |
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