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Macro-Glycoligands

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Cover of 'Macro-Glycoligands'

Table of Contents

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    Book Overview
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    Chapter 1 Synthesis of Chain-End Functionalized Glycopolymers via Cyanoxyl-Mediated Free Radical Polymerization (CMFRP)
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    Chapter 2 Protecting-Group-Free Synthesis of Well-Defined Glycopolymers Featuring Negatively Charged Oligosaccharides
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    Chapter 3 Glycopolymers Prepared by Ring-Opening Metathesis Polymerization Followed by Glycoconjugation Using a Triazole-Forming “Click” Reaction
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    Chapter 4 Protecting-Group-Free Synthesis of Glycopolymers and Their Binding Assay with Lectin and Influenza Virus
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    Chapter 5 Carbohydrate-Based Initiators for the Cationic Ring-Opening Polymerization of 2-Ethyl-2-Oxazoline
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    Chapter 6 Heterofunctional Glycopolypeptides by Combination of Thiol-Ene Chemistry and NCA Polymerization
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    Chapter 7 Preparation of Proteoglycan Mimetic Graft Copolymers
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    Chapter 8 Galactosylated Polymer Nano-objects by Polymerization-Induced Self-Assembly, Potential Drug Nanocarriers.
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    Chapter 9 Synthetic Approach to Biotinylated Glyco-Functionalized Quantum Dots: A New Fluorescent Probes for Biomedical Applications
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    Chapter 10 Surface Modification of Polydivinylbenzene Microspheres with a Fluorinated Glycopolymer Using Thiol-Halogen Click Chemistry
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    Chapter 11 Glycopolymer-Grafted Polymer Particles for Lectin Recognition
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    Chapter 12 Synthesis of Non-spherical Glycopolymer-Decorated Nanoparticles: Combing Thiol-ene with Catecholic Chemistry
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    Chapter 13 Synthetic Approach to Glycopolymer Base Nanoparticle Gold(I) Conjugate: A New Generation of Therapeutic Agents
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    Chapter 14 Multivalent Glycopolymer-Coated Gold Nanoparticles
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    Chapter 15 Modulation of Multivalent Protein Binding on Surfaces by Glycopolymer Brush Chemistry
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    Chapter 16 Oriented Immobilized Sialyloligo-macroligand Microarray
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    Chapter 17 Glycocalyx Remodeling with Glycopolymer-Based Proteoglycan Mimetics
Attention for Chapter 5: Carbohydrate-Based Initiators for the Cationic Ring-Opening Polymerization of 2-Ethyl-2-Oxazoline
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Chapter title
Carbohydrate-Based Initiators for the Cationic Ring-Opening Polymerization of 2-Ethyl-2-Oxazoline
Chapter number 5
Book title
Macro-Glycoligands
Published in
Methods in molecular biology, January 2016
DOI 10.1007/978-1-4939-3130-9_5
Pubmed ID
Book ISBNs
978-1-4939-3129-3, 978-1-4939-3130-9
Authors

Christine Weber, Michael Gottschaldt, Richard Hoogenboom, Ulrich S. Schubert

Abstract

The advancement in the field of living and controlled polymerization techniques provides the opportunity for careful bottom-up design of polymers for biomedical applications according to their specific needs. This contribution describes the detailed methodology to functionalize poly(2-ethyl-2-oxazoline), a polymer with properties very similar to polyethylene glycol, in a stereo-selective manner with a range of carbohydrates that can serve as biological targeting units. The obtained building blocks can subsequently be applied for the synthesis of more complex polymeric architectures.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 40%
Student > Ph. D. Student 1 20%
Professor 1 20%
Unknown 1 20%
Readers by discipline Count As %
Chemistry 3 60%
Unknown 2 40%