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Bioreactors in Stem Cell Biology

Overview of attention for book
Cover of 'Bioreactors in Stem Cell Biology'

Table of Contents

  1. Altmetric Badge
    Book Overview
  2. Altmetric Badge
    Chapter 309 Development of a Bladder Bioreactor for Tissue Engineering in Urology
  3. Altmetric Badge
    Chapter 310 Generation of Neural Progenitor Spheres from Human Pluripotent Stem Cells in a Suspension Bioreactor
  4. Altmetric Badge
    Chapter 311 Expansion of Human Induced Pluripotent Stem Cells in Stirred Suspension Bioreactors.
  5. Altmetric Badge
    Chapter 312 Aggregate and Microcarrier Cultures of Human Pluripotent Stem Cells in Stirred-Suspension Systems
  6. Altmetric Badge
    Chapter 314 Large-Scale Expansion and Differentiation of Mesenchymal Stem Cells in Microcarrier-Based Stirred Bioreactors
  7. Altmetric Badge
    Chapter 317 Whole-Heart Construct Cultivation Under 3D Mechanical Stimulation of the Left Ventricle
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    Chapter 318 Scalable Expansion of Human Pluripotent Stem Cell-Derived Neural Progenitors in Stirred Suspension Bioreactor Under Xeno-free Condition
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    Chapter 332 Tendon Differentiation on Decellularized Extracellular Matrix Under Cyclic Loading
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    Chapter 333 Perfusion Stirred-Tank Bioreactors for 3D Differentiation of Human Neural Stem Cells
  11. Altmetric Badge
    Chapter 334 Use of Stirred Suspension Bioreactors for Male Germ Cell Enrichment
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    Chapter 335 Multicompartmental Hollow-Fiber-Based Bioreactors for Dynamic Three-Dimensional Perfusion Culture
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    Chapter 336 A Bioreactor to Apply Multimodal Physical Stimuli to Cultured Cells
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    Chapter 337 Use of Microfluidic Technology to Monitor the Differentiation and Migration of Human ESC-Derived Neural Cells
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    Chapter 338 Expansion of Human Mesenchymal Stem Cells in a Microcarrier Bioreactor
  16. Altmetric Badge
    Chapter 340 A Microfluidic Bioreactor for Toxicity Testing of Stem Cell Derived 3D Cardiac Bodies
  17. Altmetric Badge
    Chapter 341 Novel Bioreactor Platform for Scalable Cardiomyogenic Differentiation from Pluripotent Stem Cell-Derived Embryoid Bodies
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    Chapter 353 Bioengineered Models of Solid Human Tumors for Cancer Research
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    Chapter 354 Uniform Embryoid Body Production and Enhanced Mesendoderm Differentiation with Murine Embryonic Stem Cells in a Rotary Suspension Bioreactor
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    Chapter 355 Bioreactor Expansion of Skin-Derived Precursor Schwann Cells
  21. Altmetric Badge
    Chapter 5001 Erratum to: Bioengineered Models of Solid Human Tumors for Cancer Research
Attention for Chapter 311: Expansion of Human Induced Pluripotent Stem Cells in Stirred Suspension Bioreactors.
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

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Chapter title
Expansion of Human Induced Pluripotent Stem Cells in Stirred Suspension Bioreactors.
Chapter number 311
Book title
Bioreactors in Stem Cell Biology
Published in
Methods in molecular biology, January 2016
DOI 10.1007/7651_2015_311
Pubmed ID
Book ISBNs
978-1-4939-6476-5, 978-1-4939-6478-9
Authors

Almutawaa, Walaa, Rohani, Leili, Rancourt, Derrick E, Walaa Almutawaa, Leili Rohani, Derrick E. Rancourt

Abstract

Human induced pluripotent stem cells (hiPSCs) hold great promise as a cell source for therapeutic applications and regenerative medicine. Traditionally, hiPSCs are expanded in two-dimensional static culture as colonies in the presence or absence of feeder cells. However, this expansion procedure is associated with lack of reproducibility and low cell yields. To fulfill the large cell number demand for clinical use, robust large-scale production of these cells under defined conditions is needed. Herein, we describe a scalable, low-cost protocol for expanding hiPSCs as aggregates in a lab-scale bioreactor.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 33%
Other 3 25%
Student > Master 2 17%
Professor 1 8%
Unknown 2 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 42%
Chemical Engineering 2 17%
Medicine and Dentistry 1 8%
Materials Science 1 8%
Engineering 1 8%
Other 0 0%
Unknown 2 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 September 2017.
All research outputs
#3,124,958
of 22,840,638 outputs
Outputs from Methods in molecular biology
#696
of 13,127 outputs
Outputs of similar age
#57,725
of 394,766 outputs
Outputs of similar age from Methods in molecular biology
#123
of 1,472 outputs
Altmetric has tracked 22,840,638 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,127 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 394,766 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 1,472 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.