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Natural Products in Cancer Prevention and Therapy

Overview of attention for book
Cover of 'Natural Products in Cancer Prevention and Therapy'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 336 Inhibition of UVB-Induced Nonmelanoma Skin Cancer: A Path from Tea to Caffeine to Exercise to Decreased Tissue Fat.
  3. Altmetric Badge
    Chapter 337 Chemoprotection Against Cancer by Isothiocyanates: A Focus on the Animal Models and the Protective Mechanisms
  4. Altmetric Badge
    Chapter 338 Personalizing lung cancer prevention through a reverse migration strategy.
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    Chapter 339 Keap1-nrf2 signaling: a target for cancer prevention by sulforaphane.
  6. Altmetric Badge
    Chapter 340 A Perspective on Dietary Phytochemicals and Cancer Chemoprevention: Oxidative Stress, Nrf2, and Epigenomics.
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    Chapter 341 Natural-Agent Mechanisms and Early-Phase Clinical Development
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    Chapter 342 Human Cancer Chemoprevention: Hurdles and Challenges
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    Chapter 343 Chemoprevention of Esophageal Squamous Cell Carcinoma with Berries.
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    Chapter 344 Cancer Chemopreventive and Therapeutic Potential of Guggulsterone
  11. Altmetric Badge
    Chapter 345 Cancer Prevention by Different Forms of Tocopherols.
  12. Altmetric Badge
    Chapter 360 Cancer Chemoprevention and Nutri-Epigenetics: State of the Art and Future Challenges.
Attention for Chapter 336: Inhibition of UVB-Induced Nonmelanoma Skin Cancer: A Path from Tea to Caffeine to Exercise to Decreased Tissue Fat.
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  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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Citations

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Summary X Dimensions citations
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Chapter title
Inhibition of UVB-Induced Nonmelanoma Skin Cancer: A Path from Tea to Caffeine to Exercise to Decreased Tissue Fat.
Chapter number 336
Book title
Natural Products in Cancer Prevention and Therapy
Published in
Topics in current chemistry, July 2012
DOI 10.1007/128_2012_336
Pubmed ID
22752580
Book ISBNs
978-3-64-234574-6, 978-3-64-234575-3
Authors

Conney, Allan H, Lou, You-Rong, Nghiem, Paul, Bernard, Jamie J, Wagner, George C, Lu, Yao-Ping, John M. Pezzuto, Nanjoo Suh, Allan H. Conney, You-Rong Lou, Paul Nghiem, Jamie J. Bernard, George C. Wagner, Yao-Ping Lu, Conney, Allan H., Bernard, Jamie J., Wagner, George C.

Editors

John M. Pezzuto, Nanjoo Suh

Abstract

Oral administration of green tea, black tea, or caffeine (but not the decaffeinated teas) inhibited ultraviolet B radiation (UVB)-induced skin carcinogenesis in SKH-1 mice. Studies with caffeine indicated that its inhibitory effect on the ATR/Chk1 pathway is an important mechanism for caffeine's inhibition of UVB-induced carcinogenesis. The regular teas or caffeine increased locomotor activity and decreased tissue fat. In these studies, decreased dermal fat thickness was associated with a decrease in the number of tumors per mouse. Administration of caffeine, voluntary exercise, and removal of the parametrial fat pads all stimulated UVB-induced apoptosis, inhibited UVB-induced carcinogenesis, and stimulated apoptosis in UVB-induced tumors. These results suggest that caffeine administration, voluntary exercise, and removal of the parametrial fat pads inhibit UVB-induced carcinogenesis by stimulating UVB-induced apoptosis and by enhancing apoptosis in DNA-damaged precancer cells and in cancer cells. We hypothesize that tissue fat secretes antiapoptotic adipokines that have a tumor promoting effect.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 8%
Unknown 11 92%
Readers by discipline Count As %
Agricultural and Biological Sciences 1 8%
Unknown 11 92%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2013.
All research outputs
#15,247,248
of 22,671,366 outputs
Outputs from Topics in current chemistry
#105
of 148 outputs
Outputs of similar age
#104,917
of 164,355 outputs
Outputs of similar age from Topics in current chemistry
#2
of 7 outputs
Altmetric has tracked 22,671,366 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 148 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,355 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.

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