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Molecular Profiling

Overview of attention for book
Cover of 'Molecular Profiling'

Table of Contents

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    Book Overview
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    Chapter 1 Tumor Staging and Grading: A Primer
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    Chapter 2 Innovations in Clinical Trial Design in the Era of Molecular Profiling
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    Chapter 3 Personalized Medicine: Ethical Aspects
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    Chapter 4 Antibody Validation by Western Blotting
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    Chapter 5 Scanning Electron Microscopy Sample Preparation and Imaging
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    Chapter 6 One-Step Preservation and Decalcification of Bony Tissue for Molecular Profiling
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    Chapter 7 Application of Hydrogel Nanoparticles for the Capture, Concentration, and Preservation of Low-Abundance Biomarkers
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    Chapter 8 Using Laser Capture Microdissection to Isolate Cortical Laminae in Nonhuman Primate Brain
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    Chapter 9 Western Blot Techniques
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    Chapter 10 ELISA for Monitoring Nerve Growth Factor
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    Chapter 11 Reverse Phase Protein Microarrays
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    Chapter 12 Clustering and Network Analysis of Reverse Phase Protein Array Data
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    Chapter 13 PCR: Identification of Genetic Polymorphisms
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    Chapter 14 Microsatellite Analysis for Identification of Individuals Using Bone from the Extinct Steller’s Sea Cow (Hydrodamalis gigas)
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    Chapter 15 Somatic DNA Mutation Analysis
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    Chapter 16 Optimization of Immunostaining for Prospective Image Analysis
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    Chapter 17 Fluorescence In Situ Hybridization of Cells, Chromosomes, and Formalin-Fixed Paraffin-Embedded Tissues
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    Chapter 18 High-Resolution Image Stitching as a Tool to Assess Tissue-Level Protein Distribution and Localization
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    Chapter 19 Mass Spectrometry-Based Biomarker Discovery
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    Chapter 20 Quantitative Mass Spectrometry by Isotope Dilution and Multiple Reaction Monitoring (MRM)
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    Chapter 21 LC-Mass Spectrometry for Metabolomics
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    Chapter 22 Metabolomic Bioinformatic Analysis
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    Chapter 23 Stable Isotope Quantitative N-Glycan Analysis by Liquid Separation Techniques and Mass Spectrometry
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    Chapter 24 Grant Writing Tips for Translational Research
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    Chapter 25 Inventions and Patents: A Practical Tutorial
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    Chapter 26 Product Development and Commercialization of Diagnostic or Life Science Products for Scientists and Researchers
Attention for Chapter 25: Inventions and Patents: A Practical Tutorial
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Chapter title
Inventions and Patents: A Practical Tutorial
Chapter number 25
Book title
Molecular Profiling
Published in
Methods in molecular biology, January 2017
DOI 10.1007/978-1-4939-6990-6_25
Pubmed ID
Book ISBNs
978-1-4939-6989-0, 978-1-4939-6990-6
Authors

Hina Mehta, Lille Tidwell, Lance A. Liotta

Editors

Virginia Espina

Abstract

Patents are designed to protect and encourage creativity and innovation. Patenting a biomedical discovery can be a requirement before a pharmaceutical company or biotech entity will invest in the lengthy and capital-intensive drug development and clinical trials necessary to achieve patient benefit. Although scientists and clinicians are well versed in research publication requirements, patent descriptions and claims are formatted in a manner quite different from a research paper. Patents require (a) a series of logical statements clearly delineating the boundaries of the novel aspects of the invention and (b) sufficient disclosure of the invention so that it can be reproduced by others. Patents are granted only for inventions that meet three conditions: novelty, non-obviousness, and usefulness. Recent changes to US patent law limit the scope of patentable material. Products of nature such as nucleic acids and proteins, or steps used to observe natural events, are no longer patent eligible. This chapter provides basic guidelines and definitions for inventions, inventorship, and patent filing which are summarized using a question and answer format.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 12%
Other 2 8%
Student > Doctoral Student 2 8%
Student > Master 2 8%
Researcher 2 8%
Other 5 19%
Unknown 10 38%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 15%
Business, Management and Accounting 4 15%
Pharmacology, Toxicology and Pharmaceutical Science 3 12%
Biochemistry, Genetics and Molecular Biology 2 8%
Unspecified 1 4%
Other 2 8%
Unknown 10 38%