Chapter title |
Systemic Analysis of Regulated Functional Networks.
|
---|---|
Chapter number | 21 |
Book title |
Proteomics in Systems Biology
|
Published in |
Methods in molecular biology, January 2016
|
DOI | 10.1007/978-1-4939-3341-9_21 |
Pubmed ID | |
Book ISBNs |
978-1-4939-3339-6, 978-1-4939-3341-9
|
Authors |
Hernández Sánchez, Luis Francisco, Aasebø, Elise, Selheim, Frode, Berven, Frode S, Ræder, Helge, Barsnes, Harald, Vaudel, Marc, Luis Francisco Hernández Sánchez, Elise Aasebø, Frode Selheim, Frode S. Berven, Helge Ræder, Harald Barsnes, Marc Vaudel |
Editors |
Jörg Reinders |
Abstract |
In biological and medical sciences, high throughput analytical methods are now commonly used to investigate samples of different conditions, e.g., patients versus controls. Systemic functional analyses emerged as a reference method to go beyond a list of regulated compounds, and identify activated or inactivated biological functions. This approach holds the promise for a better understanding of biological systems, of the mechanisms involved in disease progression, and thus improved diagnosis, prognosis, and treatment. In this chapter, we present a simple workflow to conduct pathway analyses on biological data using the freely available Reactome platform ( http://www.reactome.org ). |
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