| Chapter title |
Circadian clocks and metabolism.
|
|---|---|
| Chapter number | 6 |
| Book title |
Circadian Clocks
|
| Published in |
Handbook of experimental pharmacology, March 2013
|
| DOI | 10.1007/978-3-642-25950-0_6 |
| Pubmed ID | |
| Book ISBNs |
978-3-64-225949-4, 978-3-64-225950-0
|
| Authors |
Marcheva B, Ramsey KM, Peek CB, Affinati A, Maury E, Bass J, Biliana Marcheva, Kathryn M. Ramsey, Clara B. Peek, Alison Affinati, Eleonore Maury, Joseph Bass, Marcheva, Biliana, Ramsey, Kathryn M., Peek, Clara B., Affinati, Alison, Maury, Eleonore, Bass, Joseph |
| Editors |
Achim Kramer, Martha Merrow |
| Abstract |
Circadian clocks maintain periodicity in internal cycles of behavior, physiology, and metabolism, enabling organisms to anticipate the 24-h rotation of the Earth. In mammals, circadian integration of metabolic systems optimizes energy harvesting and utilization across the light/dark cycle. Disruption of clock genes has recently been linked to sleep disorders and to the development of cardiometabolic disease. Conversely, aberrant nutrient signaling affects circadian rhythms of behavior. This chapter reviews the emerging relationship between the molecular clock and metabolic systems and examines evidence that circadian disruption exerts deleterious consequences on human health. |
X Demographics
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| Mexico | 1 | 8% |
| Egypt | 1 | 8% |
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| Unknown | 6 | 46% |
Demographic breakdown
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|---|---|---|
| Members of the public | 11 | 85% |
| Practitioners (doctors, other healthcare professionals) | 1 | 8% |
| Scientists | 1 | 8% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Croatia | 1 | <1% |
| Sweden | 1 | <1% |
| Unknown | 238 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 48 | 20% |
| Student > Bachelor | 38 | 16% |
| Student > Master | 25 | 10% |
| Researcher | 23 | 9% |
| Student > Doctoral Student | 14 | 6% |
| Other | 35 | 14% |
| Unknown | 60 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 52 | 21% |
| Agricultural and Biological Sciences | 35 | 14% |
| Medicine and Dentistry | 28 | 12% |
| Neuroscience | 18 | 7% |
| Psychology | 6 | 2% |
| Other | 32 | 13% |
| Unknown | 72 | 30% |