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Circadian Clocks

Overview of attention for book
Attention for Chapter 17: Proteomic approaches in circadian biology.
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Chapter title
Proteomic approaches in circadian biology.
Chapter number 17
Book title
Circadian Clocks
Published in
Handbook of experimental pharmacology, March 2013
DOI 10.1007/978-3-642-25950-0_17
Pubmed ID
Book ISBNs
978-3-64-225949-4, 978-3-64-225950-0
Authors

Maria S. Robles, Matthias Mann

Editors

Achim Kramer, Martha Merrow

Abstract

Circadian clocks are endogenous oscillators that drive the rhythmic expression of a broad array of genes that orchestrate metabolism and physiology. Recent evidence indicates that posttranscriptional and posttranslational mechanisms play essential roles in modulating circadian gene expression, particularly for the molecular mechanism of the clock. In contrast to genetic technologies that have long been used to study circadian biology, proteomic approaches have so far been limited and, if applied at all, have used two-dimensional gel electrophoresis (2-DE). Here, we review the proteomics approaches applied to date in the circadian field, and we also discuss the exciting potential of using cutting-edge proteomics technology in circadian biology. Large-scale, quantitative protein abundance measurements will help to understand to what extent the circadian clock drives system wide rhythms of protein abundance downstream of transcription regulation.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 24%
Student > Ph. D. Student 7 19%
Student > Master 4 11%
Professor > Associate Professor 3 8%
Student > Bachelor 2 5%
Other 4 11%
Unknown 8 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 30%
Biochemistry, Genetics and Molecular Biology 8 22%
Medicine and Dentistry 3 8%
Neuroscience 2 5%
Chemistry 2 5%
Other 0 0%
Unknown 11 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2015.
All research outputs
#15,270,698
of 22,708,120 outputs
Outputs from Handbook of experimental pharmacology
#393
of 644 outputs
Outputs of similar age
#135,480
of 215,831 outputs
Outputs of similar age from Handbook of experimental pharmacology
#8
of 10 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 644 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.3. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 215,831 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.