| Chapter title |
The Long and Short Non-coding RNAs in Cancer Biology
|
|---|---|
| Chapter number | 12 |
| Book title |
The Long and Short Non-coding RNAs in Cancer Biology
|
| Published in |
Advances in experimental medicine and biology, July 2016
|
| DOI | 10.1007/978-981-10-1498-7_12 |
| Pubmed ID | |
| Book ISBNs |
978-9-81-101496-3, 978-9-81-101498-7
|
| Authors |
Li, Mengfeng, Guan, Hongyu, Mengfeng Li, Hongyu Guan |
| Editors |
Erwei Song |
| Abstract |
As transcription factors that regulate expression of a variety of genes essential for diverse physiological and pathological processes, nuclear factor kappa B (NF-κB) family molecules play important roles in the development and progression of malignant tumor, and constitutive activation of NF-κB has been evidenced in various types of tumor tissues. Underlying its pathologic role, deregulated expression and/or transactivating activity of NF-κB usually involves multiple layers of molecular mechanisms. Noncoding RNAs, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), are known to modulate expression and biological functions of regulatory proteins in a variety of cancer contexts. In this chapter, the regulatory role of miRNAs and lncRNAs in NF-κB signaling in malignant diseases will be discussed. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 33% |
| United States | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 7 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 3 | 43% |
| Researcher | 2 | 29% |
| Professor > Associate Professor | 1 | 14% |
| Student > Master | 1 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 2 | 29% |
| Biochemistry, Genetics and Molecular Biology | 1 | 14% |
| Immunology and Microbiology | 1 | 14% |
| Medicine and Dentistry | 1 | 14% |
| Neuroscience | 1 | 14% |
| Other | 0 | 0% |
| Unknown | 1 | 14% |