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Cell-Penetrating Peptides

Overview of attention for book
Cover of 'Cell-Penetrating Peptides'

Table of Contents

  1. Altmetric Badge
    Book Overview
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    Chapter 1 Classes of Cell-Penetrating Peptides.
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    Chapter 2 Cell-Penetrating Peptides
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    Chapter 3 Prediction of Cell-Penetrating Peptides
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    Chapter 4 Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.
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    Chapter 5 Investigating Membrane Interactions and Structures of CPPs.
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    Chapter 6 Determining the Effects of Membrane-Interacting Peptides on Membrane Integrity.
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    Chapter 7 Study of CPP Mechanisms by Mass Spectrometry.
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    Chapter 8 Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides
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    Chapter 9 Toxicity, Immunogenicity, Uptake, and Kinetics Methods for CPPs
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    Chapter 10 Unraveling the Mechanisms of Peptide-Mediated Delivery of Nucleic Acids Using Electron Microscopy.
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    Chapter 11 SCARA Involvement in the Uptake of Nanoparticles Formed by Cell-Penetrating Peptides
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    Chapter 12 Protein Mimicry and the Design of Bioactive Cell-Penetrating Peptides.
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    Chapter 13 Pepducins and Other Lipidated Peptides as Mechanistic Probes and Therapeutics.
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    Chapter 14 Identification and Characterization of Homing Peptides Using In Vivo Peptide Phage Display.
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    Chapter 15 The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides
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    Chapter 16 Visualizing Actin Architectures in Cells Incubated with Cell-Penetrating Peptides.
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    Chapter 17 Cell-Penetrating Peptides as Carriers for Transepithelial Drug Delivery In Vitro.
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    Chapter 18 A Pathway Toward Tumor Cell-Selective CPPs?
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    Chapter 19 PepFects and NickFects for the Intracellular Delivery of Nucleic Acids
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    Chapter 20 In Vitro Assays to Assess Exon Skipping in Duchenne Muscular Dystrophy.
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    Chapter 21 Applications of ApoB LDLR-Binding Domain Approach for the Development of CNS-Penetrating Peptides for Alzheimer's Disease.
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    Chapter 22 CPP-Based Delivery System for In Vivo Gene Delivery
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    Chapter 23 Application of CPPs for Brain Delivery
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    Chapter 24 Intracellular Delivery of Nanoparticles with Cell Penetrating Peptides.
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    Chapter 25 Cell-Penetrating Peptides
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    Chapter 26 Cell Penetrating Peptides for Chemical Biological Studies.
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    Chapter 27 Experiences with CPP-Based Self Assembling Peptide Systems for Topical Delivery of Botulinum Toxin.
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    Chapter 28 Applications of CPPs in Genome Modulation of Plants.
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    Chapter 29 DNA Transfer into Animal Cells Using Stearylated CPP Based Transfection Reagent.
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    Chapter 30 Live Cell Genomics: Cell-Specific Transcriptome Capture in Live Tissues and Cells.
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    Chapter 31 Live Cell Genomics: RNA Exon-Specific RNA-Binding Protein Isolation.
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    Chapter 32 ERRATUM TO: Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides.
Attention for Chapter 4: Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.
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Chapter title
Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.
Chapter number 4
Book title
Cell-Penetrating Peptides
Published in
Methods in molecular biology, January 2015
DOI 10.1007/978-1-4939-2806-4_4
Pubmed ID
Book ISBNs
978-1-4939-2805-7, 978-1-4939-2806-4
Authors

Ankur Gautam, Kumardeep Chaudhary, Rahul Kumar, Gajendra Pal Singh Raghava

Editors

Ülo Langel

Abstract

Cell-penetrating peptides (CPPs) have proven their potential as versatile drug delivery vehicles. Last decade has witnessed an unprecedented growth in CPP-based research, demonstrating the potential of CPPs as therapeutic candidates. In the past, many in silico algorithms have been developed for the prediction and screening of CPPs, which expedites the CPP-based research. In silico screening/prediction of CPPs followed by experimental validation seems to be a reliable, less time-consuming, and cost-effective approach. This chapter describes the prediction, screening, and designing of novel efficient CPPs using "CellPPD," an in silico tool.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
India 1 1%
Unknown 76 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 17%
Student > Ph. D. Student 12 16%
Student > Bachelor 7 9%
Student > Master 7 9%
Student > Doctoral Student 3 4%
Other 10 13%
Unknown 25 32%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 16 21%
Agricultural and Biological Sciences 16 21%
Chemistry 5 6%
Immunology and Microbiology 2 3%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 7 9%
Unknown 29 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2016.
All research outputs
#15,379,760
of 22,880,230 outputs
Outputs from Methods in molecular biology
#5,351
of 13,132 outputs
Outputs of similar age
#209,202
of 353,344 outputs
Outputs of similar age from Methods in molecular biology
#345
of 997 outputs
Altmetric has tracked 22,880,230 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,132 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 353,344 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 997 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.