Chapter title |
Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.
|
---|---|
Chapter number | 4 |
Book title |
Cell-Penetrating Peptides
|
Published in |
Methods in molecular biology, January 2015
|
DOI | 10.1007/978-1-4939-2806-4_4 |
Pubmed ID | |
Book ISBNs |
978-1-4939-2805-7, 978-1-4939-2806-4
|
Authors |
Ankur Gautam, Kumardeep Chaudhary, Rahul Kumar, Gajendra Pal Singh Raghava |
Editors |
Ülo Langel |
Abstract |
Cell-penetrating peptides (CPPs) have proven their potential as versatile drug delivery vehicles. Last decade has witnessed an unprecedented growth in CPP-based research, demonstrating the potential of CPPs as therapeutic candidates. In the past, many in silico algorithms have been developed for the prediction and screening of CPPs, which expedites the CPP-based research. In silico screening/prediction of CPPs followed by experimental validation seems to be a reliable, less time-consuming, and cost-effective approach. This chapter describes the prediction, screening, and designing of novel efficient CPPs using "CellPPD," an in silico tool. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 1% |
Unknown | 76 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 13 | 17% |
Student > Ph. D. Student | 12 | 16% |
Student > Bachelor | 7 | 9% |
Student > Master | 7 | 9% |
Student > Doctoral Student | 3 | 4% |
Other | 10 | 13% |
Unknown | 25 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 16 | 21% |
Agricultural and Biological Sciences | 16 | 21% |
Chemistry | 5 | 6% |
Immunology and Microbiology | 2 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 7 | 9% |
Unknown | 29 | 38% |